CLEVELAND (AP) -- Giovanny Urshela hit his first major league home run, Shaun Marcum and his bullpen combined on a two-hitter and the Cleveland Indians beat the Seattle Mariners 6-0 on Thursday.
A 23-year-old from Colombia who made his big league debut Tuesday, Urshela grounded an RBI single past shortstop Brad Miller in a four-run third, the first batter after Tom Wilhelmsen relieved J.A. Happ (3-2). Cleveland saved the ball for Urshela, who then hit a solo homer off Vidal Nuno in the sixth.
That ball just cleared the 19-foot fence in left and rebounded onto the field, providing a second memento for Urshela, who smiled widely as he slapped hands with teammates in the dugout.
Urshela is 2 for 8 with three RBIs. He was called up from Triple-A Columbus when third baseman Lonnie Chisenhall was sent down.
Marcum (3-1) retired his first nine batters and already led 5-0 before hitting Logan Morrison on the back of his right leg leading off the fourth. Mark Trumbo grounded a single just out of the reach of Urshela at third and shortstop Mike Aviles with out one in the fifth. Robinson Cano, hitting .214 since May 9 (25 for 117), doubled to right-center leading off the seventh. The Mariners' final nine batters then made out.
Marcum struck out five and walked none. Zach McAllister and Cody Allen followed with perfect innings for Cleveland, which broke a three-game losing streak.
Seattle (27-33) has lost nine of its last 12 games and scored more than three runs just once in its last 15 games. Nelson Cruz, who leads the AL with 18 home runs, missed his second straight game because of back spasms.
Happ (3-2) allowed four runs, six hits and two walks in 2 1-3 innings. Brandon Moss chased him with an RBI single, and Roberto Perez capped the burst with a two-run single.
Zach Walters's RBI single put Cleveland ahead in the second.
Morrison was 0 for 3, ending his career-high hitting streak at 16 games.
Indians second baseman Jason Kipnis didn't start for the first time this season after playing in Cleveland's first 58 games. Kipnis is second in the AL in hitting with a .333 average.
Mariners: Cruz is expected to return Friday when Seattle opens a three-game series in Houston.
Indians: RHP Scott Atchison (sprained left ankle) is likely to be activated on Friday or Saturday. He threw a scoreless inning in a rehab assignment for Double-A Akron on Wednesday. .
Mariners: RHP Felix Hernandez (9-2), who leads the AL in wins, starts Friday against Houston.
Indians: RHP Danny Salazar (6-1), fourth in the AL with 81 strikeouts, opens a three-game series Friday at Detroit.