Miguel Cabrera started the day with his 400th homer.
More than five hours later, Joakim Soria finished it by striking out Yadier Molina.
At the end, the Tigers had a second-straight victory over the St. Louis Cardinals, a team that came into the series with only three losses at home.
"It was a long day with the rain, but this was a big team victory," Brad Ausmus said. "We got some big hits, some great defense and some great pitching in key spots. Everyone out there contributed."
The Tigers got a lot of help from the Cardinals, who looked like a Little League team on the basepaths. In the seventh inning, with the score tied at 3, Jason Heyward was on second when Randal Grichuk crushed a double off the left-centerfield fence.
Heyward, who should have scored standing up, only made it to third, having waited to tag up on a ball hit 10 feet over Yoenis Cespedes' head. David Price and Angel Nesbitt got out of the inning.
In the eighth, Pete Kozma was on second base with no one out and Joba Chamberlain looking uncomfortable on the mound. Reynolds popped up behind first base, and Cabrera made a nice running catch in foul territory.
Kozma, who apparently didn't pay attention to the scouting report on the Tigers, was then thrown out by 10 feet trying to take third base on Cabrera's strong arm. Molina followed with a single that would have easily scored Kozma from second, but the game was still tied at three.
"In that situation, you don't have time to look at the runner," Cabrera said. "If you take a second to see what he's doing, he's probably going to be safe. You have to just go on your instincts and make the throw."
Even in the bottom of the 10th, after the Tigers had taken a 4-3 lead on Jose Iglesias's two-out single, Matt Holliday led off with a single, but was easily thrown out by Rajai Davis when he tried to stretch it into a double.
The Cardinals were making bad decisions, but the Tigers still had to execute in order to take advantage.
"We know the Cardinals are an aggressive team, so we were ready for them to take chances," Cabrera said. "That's how they play baseball, and they are very good, but we made the big plays we needed."
While St. Louis was stumbling around the basepaths, the Tigers went six scoreless innings after taking a 3-2 lead in the third, but finally broke through in the 10th.
With two on and runners on the corners, Iglesias took a 2-1 pitch that looked like it was clearly low and outside. Home plate umpire Vic Carapazza, who had a large strike zone all day, called it a strike, and Iglesias looked back to register his displeasure.
His anger didn't last long, as he looped Matt Belisle's next pitch into right-centerfield to put the Tigers back in front.
"I told him it was low, but then I turned the page and got focused again," he said. "It was a big situation, and I wanted to try to put something into play and give us the lead."
The teams finish the weekend with a Sunday-night game, but the Tigers have already become the first visiting team this season to win a series at Busch Stadium.
They might get another chance in October.
