Keith Clanton's three-point play with 4 seconds to go lifted Central Florida over Memphis 68-67 Wednesday night and gave the Knights their first victory over the Tigers in 11 meetings.
Clanton finished with 23 points and Marcus Jordan added 20 for UCF (14-4, 4-1 Conference USA).
Will Barton had 24 points and Chris Crawford scored 12 for the Tigers (12-6, 3-1).
Jordan's driving layup with 1:21 left, the Knights' first field goal in more than eight minutes, put UCF up 65-64.
Memphis backup Joe Jackson just beat the shot clock with a 3-pointer to give the Tigers a 67-65 lead with 42 seconds to play, but they couldn't hang on.
UCF started the second half with a 13-3 run to push a 3-point halftime lead to 54-41after Josh Crittle's turnaround jumper with 16:01 left.
Memphis responded with11 straight points and eventually led 64-63 on Crawford's foul-line jumper with 4:11 remaining.