Nych Smith added 22 points for the Eagles. Pickett made 9 of 11 shots.
Adam Flagler had 23 points for the Blue Hose (15-12, 7-5). Francois Lewis added 23 points and eight rebounds. Cory Hightower had 16 points and eight rebounds. Davon Bell had 10 points, eight rebounds and 13 of Presbyterian's 15 assists.
The Eagles leveled the season series against the Blue Hose with the win. Presbyterian defeated Winthrop 99-91 on Jan. 26.
Winthrop plays Gardner-Webb on the road on Saturday. Presbyterian plays Campbell at home on Saturday.