The Eagles held the Ragin' Cajuns to 28.6 percent shooting, the lowest mark of the season for a Georgia Southern opponent.
Jalen Johnson had 15 points for the Ragin' Cajuns (7-11, 2-5). Tirus Smith added 12 points and three blocks. Dou Gueye had seven rebounds.
Cedric Russell, who was second on the Ragin' Cajuns in scoring heading into the matchup with 14 points per game, was held to only five points on 2-of-14 shooting.
Georgia Southern matches up against Troy on the road on Thursday. Louisiana-Lafayette matches up against Texas-Arlington at home on Thursday.