Chiefs vs. 49ers highlights: K.C. rides smothering defense to 28-18 win over S.F.

Oct 20, 2024 - 7:28p ET

Takeaways: Chiefs defense is still elite, while 49ers have more injuries to navigate

Live Coverage for this has ended

Oct 20, 2024 - 7:19p ET

Tom Brady impressed with youngsters on Chiefs defense

Oct 20, 2024 - 7:17p ET

Star 49ers OL Trent Williams ejected as game gets chippy

Oct 20, 2024 - 7:14p ET

Mecole Hardman finds end zone again vs. 49ers

Oct 20, 2024 - 7:05p ET

Brock Purdy leads 49ers into red zone — and is picked again

Oct 20, 2024 - 6:49p ET

Patrick Mahomes' legs set up crucial touchdown

Oct 20, 2024 - 6:37p ET

Brock Purdy throws second interception of the game

Oct 20, 2024 - 6:28p ET

Which QB can find the next gear?

Oct 20, 2024 - 6:20p ET

Tom Brady's advice to 49ers: 'Run the football'

Oct 20, 2024 - 6:16p ET

Purdy's, 49ers' aggressiveness pays off for their first TD of game

Oct 20, 2024 - 6:11p ET

Patrick Mahomes picked off again

Oct 20, 2024 - 6:07p ET

Halftime: Red zone execution difference in game so far as Chiefs lead

Oct 20, 2024 - 5:56p ET

Brandon Aiyuk leaves with knee injury just before halftime

Oct 20, 2024 - 5:48p ET

Ricky Pearsall makes first NFL catch, gets standing ovation

Oct 20, 2024 - 5:36p ET

49ers offense continues to scuffle

Oct 20, 2024 - 5:31p ET

Kareem Hunt's second TD in as many drives increases Chiefs' lead

Oct 20, 2024 - 5:15p ET

Kansas City in the end zone first!

Oct 20, 2024 - 5:05p ET

Tom Brady: Points will be 'hard to come by' in defensive battle

Oct 20, 2024 - 4:56p ET

Which offense can strike first?

Oct 20, 2024 - 4:55p ET

49ers return the favor, picking off Mahomes — and Brady breaks it down

Oct 20, 2024 - 4:42p ET

Justin Reid picks off Brock Purdy

Oct 20, 2024 - 4:40p ET

Defenses standing up early

Oct 20, 2024 - 4:09p ET

GOAT QB, WR holding court pregame

Oct 20, 2024 - 4:02p ET

Preview: These aren't last year's Chiefs and 49ers

Live Coverage for this began on Oct 20, 2024 - 7:57p ET