2025 NFL Divisional Round Predictions, Betting Odds & TV Schedule

The Divisional NFL Playoffs lineup has several top-tier games, including a matchup between the San Francisco 49ers and the Seattle Seahawks.

For analysis of all the important matchups in the NFL this weekend, read our betting odds preview below.

Check out the full NFL schedule on FOX Sports!

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This Week's Betting Lines & Game Info

Denver Broncos vs. Buffalo Bills

Odds & Prediction

• Spread: Broncos (-1.5)
• Moneyline: Broncos -119, Bills -101
• Total: 45.5 points
• Prediction: Broncos 24, Bills 23

How to Watch

• Game Date: Saturday, Jan. 17
• Game Time: 4:30 p.m. ET
• TV Channel: CBS
• Box Score
• Location: Denver, Colorado

Seattle Seahawks vs. San Francisco 49ers

Odds & Prediction

• Spread: Seahawks (-6.5)
• Moneyline: Seahawks -296, 49ers +239
• Total: 44.5 points
• Prediction: Seahawks 28, 49ers 19

How to Watch

• Game Date: Saturday, Jan. 17
• Game Time: 8 p.m. ET
• TV Channel: FOX
• Streaming: FOXSports.com, FOX Sports App and FOX One (Try free for 7 days)
• Location: Seattle, Washington

New England Patriots vs. Houston Texans

Odds & Prediction

• Spread: Patriots (-3)
• Moneyline: Patriots -180, Texans +151
• Total: 41 points
• Prediction: Patriots 23, Texans 22

How to Watch

• Game Date: Sunday, Jan. 18
• Game Time: 3 p.m. ET
• TV Channel: ABC/ESPN
• Box Score
• Location: Foxborough, Massachusetts

Chicago Bears vs. Los Angeles Rams

Odds & Prediction

• Spread: Rams (-3.5)
• Moneyline: Rams -200, Bears +166
• Total: 49 points
• Prediction: Rams 31, Bears 20

How to Watch

• Game Date: Sunday, Jan. 18
• Game Time: 6:30 p.m. ET
• TV Channel: NBC/Peacock
• Box Score
• Location: Chicago, Illinois

Learn more about today's games on FOX Sports.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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