
2025-26 Buffalo Bills Odds: Odds to win Super Bowl, NFL Playoffs, Division
Updated Jan. 15, 2026 12:31 p.m. ET
Data Skrive
The Buffalo Bills have +650 odds to win the Super Bowl, fourth-best in the league as of Jan. 15.
In their last outing, the Bills won 27-24 over the Jacksonville Jaguars. Josh Allen threw for 273 yards, with one touchdown and no interceptions on 28-of-35 passing (80.0%). He also added 11 carries for 33 yards and two rushing touchdowns. James Cook took 15 carries for 46 yards (3.1 yards per carry), while adding two receptions for five yards in the passing game. Khalil Shakir had 12 receptions for 82 yards (6.8 per catch).
Bills Postseason Odds
- Odds to win the Super Bowl: +650 (Bet $100 to win $650)
Learn more about the Buffalo Bills on Fox Sports.
Bills Super Bowl Odds Insights
- As far as winning the Super Bowl, the Bills (+650) rank better according to oddsmakers (fourth-best in NFL) than they do in our computer rankings (seventh-best).
- The Bills' current Super Bowl odds (+650) are the same as they were in the preseason (+650).
- At +650, the Bills have a 13.3% chance of winning the Super Bowl.
Bills Betting Insights
- The Bills have compiled an 8-9-0 record against the spread this season.
- Buffalo and its opponent have combined to hit the over nine out of 17 times this season.
- The Bills have gone 10-5 in games they were favored on the moneyline (winning 66.7% of those games).
- Buffalo has won both games it has played as underdogs this season.
Bills Top Players
- Allen has passed for 3,668 yards (319-for-460), with 25 touchdowns and 10 interceptions (229.3 YPG). He's also run the ball 112 times for 579 yards and 14 scores, averaging 36.2 YPG.
- Allen's game status for Saturday's Divisional matchup against the Broncos is currently unknown. He was a full participant in the Bills' last practice.
- Cook has 309 attempts for a team-leading 1,621 rushing yards (95.4 per game) and 12 touchdowns. He also has 33 catches for 291 receiving yards (17.1 per game) and two touchdowns.
- Shakir has 72 receptions for a team-high 719 yards (44.9 per game) and four touchdowns.
- Dalton Kincaid has also chipped in with 571 yards, on 39 catches plus five touchdowns. He puts up 47.6 receiving yards per game.
- Kincaid's game status for Saturday's Divisional matchup against the Broncos is unknown. He was a limited participant in the Bills' last practice.
- Dawson Knox is averaging 26.1 yards per game, racking up 36 receptions (49 targets) for 417 yards and four touchdowns.
- Greg Rousseau has 7.0 sacks to lead the team, and has also added 6.0 TFL and 46 tackles.
- Rousseau's status for Saturday is currently unknown. He was a limited participant in the Bills' most recent practice.
- Cole Bishop leads the team in both tackles and interceptions, totaling 85 tackles, 4.0 TFL, two sacks, and three interceptions over the course of the current campaign.
Bills 2025-26 Schedule
| Opponent | Week | Date | Opponent Power Ranking | Favorite | Total |
|---|---|---|---|---|---|
| Ravens | 1 | Sept. 7 | 13th | Ravens (-2.5) | 50.5 |
| @ Jets | 2 | Sept. 14 | 32nd | Bills (-6.5) | 47.5 |
| Dolphins | 3 | Sept. 18 | 26th | Bills (-12.5) | 50.5 |
| Saints | 4 | Sept. 28 | 22nd | Bills (-14.5) | 48.5 |
| Patriots | 5 | Oct. 5 | 6th | Bills (-7.5) | 50.5 |
| @ Falcons | 6 | Oct. 13 | 19th | Bills (-4.5) | 50.5 |
| @ Panthers | 8 | Oct. 26 | 20th | Bills (-7.5) | 47.5 |
| Chiefs | 9 | Nov. 2 | 21st | Chiefs (-1.5) | 53.5 |
| @ Dolphins | 10 | Nov. 9 | 26th | Bills (-7.5) | 50.5 |
| Buccaneers | 11 | Nov. 16 | 18th | Bills (-6.5) | 46.5 |
| @ Texans | 12 | Nov. 20 | 3rd | Bills (-5.5) | 44.5 |
| @ Steelers | 13 | Nov. 30 | 17th | Bills (-3) | 44.5 |
| Bengals | 14 | Dec. 7 | 24th | Bills (-6.5) | 54.5 |
| @ Patriots | 15 | Dec. 14 | 6th | Bills (-2.5) | 49.5 |
| @ Browns | 16 | Dec. 21 | 29th | Bills (-10.5) | 41.5 |
| Eagles | 17 | Dec. 28 | 9th | Bills (-3) | 45.5 |
| Jets | 18 | Jan. 4 | 32nd | Bills (-12.5) | 39.5 |
| @ Jaguars | WC | Jan. 11 | 4th | Jaguars (-1.5) | 51.5 |
| @ Broncos | Div. Round | Jan. 17 | 8th | Broncos (-1.5) | 46.5 |
FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.
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