2025-26 Buffalo Bills Odds: Odds to win Super Bowl, NFL Playoffs, Division

Updated Jan. 14, 2026 9:31 p.m. ET

Data Skrive

The Buffalo Bills at the moment have the fourth-best odds to win the Super Bowl in the entire league at +650.

The Bills picked up a 27-24 win over the Jacksonville Jaguars in their last outing. Josh Allen had 273 yards on 28-of-35 passing (80.0%), with one touchdown and no interceptions. He also carried the ball 11 times for 33 yards and two rushing touchdowns. James Cook carried the ball 15 times for 46 yards (3.1 yards per carry). He added two receptions for five yards. Khalil Shakir led the receiving charge, catching 12 passes for 82 yards.

Bills Postseason Odds

Odds to win the Super Bowl: +650 (Bet $100 to win $650)

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Bills Super Bowl Odds Insights

As far as winning the Super Bowl, the Bills (+650) rank better according to oddsmakers (fourth-best in NFL) than they do in our computer rankings (seventh-best).
The Bills' updated Super Bowl odds, according to oddsmakers, are +650, which are the same odds as they had before the season started (+650).
The Bills, based on their updated odds (+650), sport a 13.3% chance of winning the Super Bowl.

Bills Betting Insights

The Bills have covered eight times in 17 matchups with a spread this season.
In Buffalo's 17 games this season, the combined scoring has gone over the point total nine times.
The Bills have been the moneyline favorite 15 total times this season. They've finished 10-5 in those games.
Buffalo has won both games it has played as underdogs this season.

Bills Top Players

This year Allen has recorded 3,668 yards through the air (229.3 yards per game) while completing 69.3% of his passes, with 25 touchdowns and 10 interceptions. He also has 579 yards on the ground on 112 carries (plus 14 scores), averaging 36.2 yards per game.
Allen's game status for Saturday's Divisional matchup against the Broncos is currently unknown. He was a full participant in the Bills' last practice.
Cook has run for a team-best 1,621 yards (95.4 YPG) and 12 touchdowns. He also has 291 receiving yards on 33 catches and two touchdowns.
Shakir has 72 receptions for a team-high 719 yards (44.9 per game) and four touchdowns.
Dalton Kincaid has 39 catches for 571 yards (47.6 per game) and five touchdowns.
Kincaid's status for Saturday is currently unknown. He was a limited participant in the Bills' most recent practice.
Dawson Knox is averaging 26.1 yards per game, racking up 36 receptions (49 targets) for 417 yards and four touchdowns.
Greg Rousseau has collected a team-leading 7.0 sacks, while adding 6.0 TFL and 46 tackles.
Rousseau's game status for Saturday's Divisional matchup against the Broncos is unknown. He was a limited participant in the Bills' last practice.
Cole Bishop leads the team in both tackles and interceptions, totaling 85 tackles, 4.0 TFL, two sacks, and three interceptions over the current campaign.

Bills 2025-26 Schedule

Opponent	Week	Date	Opponent Power Ranking	Favorite	Total
Ravens	1	Sept. 7	13th	Ravens (-2.5)	50.5
@ Jets	2	Sept. 14	32nd	Bills (-6.5)	47.5
Dolphins	3	Sept. 18	26th	Bills (-12.5)	50.5
Saints	4	Sept. 28	22nd	Bills (-14.5)	48.5
Patriots	5	Oct. 5	6th	Bills (-7.5)	50.5
@ Falcons	6	Oct. 13	19th	Bills (-4.5)	50.5
@ Panthers	8	Oct. 26	20th	Bills (-7.5)	47.5
Chiefs	9	Nov. 2	21st	Chiefs (-1.5)	53.5
@ Dolphins	10	Nov. 9	26th	Bills (-7.5)	50.5
Buccaneers	11	Nov. 16	18th	Bills (-6.5)	46.5
@ Texans	12	Nov. 20	3rd	Bills (-5.5)	44.5
@ Steelers	13	Nov. 30	17th	Bills (-3)	44.5
Bengals	14	Dec. 7	24th	Bills (-6.5)	54.5
@ Patriots	15	Dec. 14	6th	Bills (-2.5)	49.5
@ Browns	16	Dec. 21	29th	Bills (-10.5)	41.5
Eagles	17	Dec. 28	9th	Bills (-3)	45.5
Jets	18	Jan. 4	32nd	Bills (-12.5)	39.5
@ Jaguars	WC	Jan. 11	4th	Jaguars (-1.5)	51.5
@ Broncos	Div. Round	Jan. 17	8th	Broncos (-1.5)	46.5