Reds vs. Rays Prediction, Odds, Picks - July 25

Elly De La Cruz and the Cincinnati Reds will square off against Junior Caminero and the Tampa Bay Rays at Great American Ball Park in the first of a three-game series, on Friday at 7:10 p.m. ET. The favored Reds have -112 moneyline odds against the underdog Rays, who are listed at -107. Tampa Bay is the favorite on the run line (-1.5). The matchup's over/under has been set at 9.5 runs.

Check out everything you need to know from a betting perspective on the Reds-Rays game, regarding the run line, moneyline and total, plus expert picks.

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Reds vs. Rays Game Information & Odds

• When: Friday, July 25, 2025 at 7:10 p.m. ET
• Where: Great American Ball Park in Cincinnati, Ohio
• How to watch on TV: FDSOH and FDSSUN

Reds vs. Rays Prediction

• Score Prediction: Reds 5, Rays 4
• Total Prediction: Under 9.5 runs
• Win Probabilities: Reds 51%, Rays 49%

Reds vs. Rays Betting Insights

• This season, the Reds have been favored 46 times and won 23, or 50%, of those games.
• Cincinnati is 22-21 this season when entering a game favored by -112 or more on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Reds have a 52.8% chance to win.
• The Rays have been victorious in 21, or 44.7%, of the 47 contests they have been chosen as underdogs in this season.
• This season, Tampa Bay has come away with a win 20 times in 42 chances when named as an underdog of at least -107 or longer on the moneyline.
• Sportsbooks have implied with the moneyline set for this matchup that the Rays have a 51.7% chance of pulling out a win.

Reds Recent Betting Performance

• The Reds were the moneyline favorite in seven of their last 10 games, and they went 4-3 in those matchups.
• In their last 10 matchups (all 10 of them had set totals), the Reds and their opponents combined to go over the run total two times.
• The Reds' ATS record is 6-4-0 over their past 10 games.

Reds Recent Stats

Reds Player Insights

• Not only does De La Cruz lead the Reds in hitting with his .276 average, he also is their foremost power hitter with 18 home runs and 65 RBI.
• In all of Major League Baseball, De La Cruz ranks 34th in homers and 16th in RBI.
• TJ Friedl is batting .265 with 15 doubles, two triples, nine home runs and 48 walks.
• Friedl is 145th in home runs and 171st in RBI among all batters in MLB.
• Spencer Steer is hitting .246 with 15 doubles, a triple, 11 home runs and 25 walks.
• Matt McLain is hitting .220 with 11 doubles, 11 home runs and 37 walks.
• McLain has recorded at least one hit in nine games in a row. During his last 10 outings he is batting .351 with two doubles, a home run, four walks and three RBIs.

Reds Team Props

Rays Recent Betting Performance

• In four games as underdogs over the last 10 matchups, the Rays have a record of 0-4.
• In their last 10 games with a total, the Rays and their opponents have failed to hit the over seven times.
• The Rays have won two of their last 10 games against the spread.

Rays Recent Stats

Rays Player Insights

• Yandy Diaz is hitting .290 with 19 doubles, a triple, 17 home runs and 34 walks, while getting on base at a rate of .350.
• Diaz is 44th in homers and 26th in RBI among all batters in the big leagues.
• Caminero has been a reliable source of runs this year, leading the lineup with 26 home runs and 68 runs batted in.
• Caminero ranks seventh among all hitters in the big leagues in homers, and 14th in RBI.
• Jonathan Aranda leads the Rays with a team-high batting average of .318.
• Chandler Simpson is hitting .308 with seven doubles, a triple and 12 walks.

Rays Team Props

2025 MLB All-Star Game: Full Home Run Swing-Off | MLB on FOX

Watch the full Home Run Swing-off between the American League and the National League in the 2025 MLB All-Star Game.

FOX Sports created this story using technology provided by Data Skrive and data from Sportradar.

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