SAN DIEGO (AP) -- The San Diego Padres couldn't break through against Tsuyoshi Wada and the Chicago Cubs enough to give Tyson Ross the victory.
Ross pitched well for seven innings but the Padres lost 3-2 on Wednesday night.
"He gave us every opportunity to win. We had the opportunities but we just didn't get the big hit," manager Bud Black said.
Ross (2-4) allowed three runs and four hits in seven innings, struck out eight and walked three.
Wada struck out nine in 4 2-3 innings in his season debut and Kris Bryant drove in the go-ahead run with a sacrifice fly in the fifth for the Cubs.
Wada opened the season on the disabled list with a left groin strain and made six rehab starts. He struck out seven of the first nine Padres batters.
His only mistake was allowing a two-run homer to Justin Upton to straightaway center field to give the Padres a 2-1 lead with two outs in the fourth. It was his team-leading 11th, and Derek Norris was aboard on a one-out single.
"We've seen him before, but he was probably tonight a little sneakier than what I remember," Black said. " I think the fastball had a little giddy up on it. He was really painting the corners, I thought, early in the game, a lot of called strikes, a lot of called third strikes. A little bit of hop in the hitting area tonight. We knew the mix of pitches that was coming but he was dotting early."
The Cubs retook the lead in the fifth against Tyson Ross (2-4). Wada drew a leadoff walk and scored on Dexter Fowler's triple to right, just beating the relay throw by Jedd Gyorko. Fowler came in on Bryant's sac fly to left.
Wada allowed two runs and four hits.
Justin Grimm (1-0) got the win after pitching 1 1-3 scoreless innings. He struck out three and walked two. Hector Rondon pitched the ninth for his ninth save in 11 chances, striking out Abraham Almonte with a runner on third to end the game.
The Cubs took a 1-0 lead in the first when Bryant singled with one out, advanced when Anthony Rizzo was hit by a pitch, stole third and scored on Starlin Castro's groundout.
Ross (2-4) allowed three runs and four hits in seven innings, struck out eight and walked three.
UP NEXT
Cubs: RHP Kyle Hendricks (0-1, 5.15) is scheduled to start the finale of the three-game series. He had a no-decision in the Cubs' 7-6, 11-inning victory against San Diego at Wrigley Field on April 18.
Padres: RHP Odrisamer Despaigne (2-2, 6.75) gets another chance after allowing seven runs and seven hits in three innings of a 10-0 loss to the Washington Nationals on Friday night.
