Rashad Green scored 19 points, including 17 in the first half when he made all seven of his field goal attempts, leading San Francisco to a 104-70 drubbing of Portland Thursday night.
San Francisco (11-8, 1-4 WCC) scored their most points in a game since beating Holy Names 129-64 on Jan. 2, 2010.
Angelo Caloiaro had 16 points, all in the second half, and Dominique O'Connor came off the bench to score 16 for San Francisco, which won its first conference game of the year after losing its first four.
Ryan Nicholas scored 12 points and Tim Douglas added 11 for the Pilots (5-12, 2-2).
Green finished 8 for 9 from the field and did not miss on two attempts from 3-point range.
The Dons shot 67.2 percent from the field, making 39 of 58 shots.