Leroy Nobles scored 24 points and Christian Siakam added 18 points and 11 rebounds to lead IUPUI to a 78-57 win over Centenary on Saturday.
The Jaguars (18-13, 12-6 Summit League) never trailed in the regular-season finale for both teams.
The Gentlemen (1-29, 1-17), coming off a 73-60 win over Western Illinois on Thursday that snapped Division I's longest losing streak at 33 games, committed 21 turnovers, resulting in 32 IUPUI points.
The Jaguars led 29-19 at halftime and held a double-digit lead throughout the second half for all but 17 seconds. After a Leo Davis layup made it 40-32, Nobles hit a 3-pointer with 14:30 left.
Centenary shot 57.7 percent in the second half (15 of 26), but IUPUI was better, at 65.5 percent (19 of 29). The Jaguars hit 9 of 21 3s and made 13 of 14 free throws, with Nobles hitting 9 of 10.
Davis led the Gentlemen with 14 points.
