DiJuan Harris hit a tiebreaking jumper with 3 seconds left in overtime and Charlotte didn't need to hit a 3-pointer to outlast Saint Louis 63-61 on Sunday and hand the Billikens their first Atlantic 10 loss.
In a frantic finish, Kyle Cassity hit a tying 3-pointer for Saint Louis with 16.7 seconds left.
But Harris pushed the ball up the floor, used a crossover dribble to create some space, and knocked down a shot just left of the foul line. Kwamain Mitchell's desperation halfcourt heave was off the mark at the buzzer.
Shamari Spears had 16 points and 13 rebounds for the 49ers (12-5, 2-1), who finished 0-for-7 from 3-point range. That ended the nation's ninth longest streak of hitting at least one 3 at 630 games, dating to the 1988-89 season.
Jon Smith scored a career-high 15 points for the Billikens (11-6, 2-1), who won in double overtime at Duquesne on Wednesday.