New Reading signings Daniel Carrico and Hope Akpan are poised to make their debuts against West Brom on Saturday.
Jason Roberts continues to be troubled by a hip problem, while Hal Robson-Kanu is a doubt with a knee injury. Mikele Leigertwood could also miss out with an unspecified knock.
Alex McCarthy is making encouraging progress following shoulder surgery and should return before the end of the season.
West Brom winger Jerome Thomas is in contention to replace long-term knee injury victim Zoltan Gera at the Madejski Stadium.
Thomas proved his fitness after an injury-hit start to the season during a loan spell at Leeds and appeared as a substitute during the Baggies' FA Cup tie at QPR last weekend.
Defenders Jonas Olsson (groin), Steven Reid (ankle) and Goran Popov (hamstring) plus midfielder Claudio Yacob (hamstring) remain doubtful while Youssouf Mulumbu is on Africa Cup of Nations duty with DR Congo.
Regan made his claims as he responded to comments by former SFA president George Peat, who claims he and Scottish Premier League chief executive Neil Doncaster are out of touch with Scottish football.
Peat had insisted that the new 12-12-18 plan to restructure the Scottish league system was not backed by football supporters.
However, Regan insists the new joint proposals from the SPL and the Scottish Football League, which he and the SFA helped broker, will benefit the game north of the border and defended his own reputation.
He told the Daily Record: "I'd say I have delivered more in the last two years than the SFA has delivered in the previous two decades.
"George has his own view but it's disappointing to hear his comments because he was instrumental in my appointment.
"He has seen the benefits and his legacy will be the implementation of the McLeish Report which I have delivered for him. My credibility is not at stake."