Germany, the Netherlands and Spain are among the sides looking to continue perfect starts to European Championship qualifying on Tuesday.
The trio top their groups, and Spain is progressing so serenely that its latest opponent, Scotland, has already acknowledged that it is playing only for second place and a playoff spot.
Scotland has two points fewer than Spain ahead of its meeting with the world and European champion in Glasgow but has played one game more.
Germany is at Kazakhstan and the Netherlands host Sweden, which has won both of its games so far.
England hosts surprise Group G leader Montenegro, while Italy welcomes Serbia and resurgent France is at home to Luxembourg.
Spain tops Group I with six points after beating Lithuania 3-1 in Friday's qualifying round but did not score until the second half, conceding an equalizer before prevailing.
Valencia striker Aritz Aduriz, who made his debut as a late substitute, was among the players to acknowledge dissatisfaction with the performance.
"I was happy we attained our objective, which was to acquire three points," Aduriz said. "However, I have not been as at ease as I would have liked.
"I think I was a bit too relaxed in some moments. I'm going to train hard in the coming days and then I'll see if I'm lucky enough to get some minutes against Scotland."
The player Aduriz replaced, Fernando Llorente, is likely to start again after scoring two headers against Lithuania, while midfielder Xabi Alonso is expected to be fit after missing Lithuania because of 'flu.
Coach Vicente Del Bosque said defender Sergio Ramos, who was replaced in the 82nd by Alvaro Arbeloa after limping heavily, only bruised his ankle.
Del Bosque is anticipating another tough game against a lower-ranked opponent. He said Lithuania made it difficult for Spain to play its normal fast-passing game, forcing the team into a more orthodox style.
"They narrowed the field and we found it difficult to receive balls," Del Bosque said. "We tried to play our one-two passing game but eventually our goals came from three crosses. It's another possibility, there's nothing better than a good cross to make a good strike."
Scotland's players are anticipating a difficult match whatever style Spain employs at Hampden Park.
"We are still on course for finishing second," Scotland defender Gary Caldwell said. "That was probably always the objective. Spain on Tuesday is a game we will go into and give everything.
"Everyone in the world wouldn't expect us to get anything and that's when Scotland are usually at their best. So we can have a right go on Tuesday night."
Also in Group I, the Czech Republic aims to follow Friday's 1-0 win over Scotland with victory at lowly Liechtenstein.
Germany beat Turkey, supposedly its closest Group A rival, 3-0 on Friday and should have little problem obtaining a fourth straight competitive win at Kazakhstan. Any slip-up could give second-place Austria the chance to close a three-point gap when it meets Belgium in Brussels.
The Netherlands' game against Sweden is likely to be its hardest so far in Group E.
The World Cup runner-up has won its three games by a combined margin of 8-1, but Sweden has gone one better - winning its two matches by a total of 8-0.
Sweden captain Zlatan Ibrahimovic and forward Johan Elmander both missed training on Friday, when Sweden was one of the few teams not to play - but coach Erik Hamren said they were just taking "precautionary measures" and the pair trained on Saturday.
"It's been amazing quality in training," Hamren said. "Good focus and good humor."
But experienced defender Olof Mellberg is suspended after a red card in Sweden's 6-0 win against San Marino. Andreas Granqvist, Petter Hansson and Jonas Olsson will vie to take his place at the heart of Sweden's defense, most likely alongside Daniel Majstorovic.
England's squad was depleted by the withdrawal because of injury of winger Aaron Lennon and defender Phil Jagielka, but coach Fabio Capello is hoping to have Wayne Rooney fit after an ankle injury ruled him out of Manchester United's past two games and threatened his participation.
England has two wins from two games but its rest on Friday allowed Montenegro to pull three points clear with a 1-0 victory over Switzerland in Podgorica.
Switzerland is last in the five-team group but coach Ottmar Hitzfeld insists all is not lost ahead of Wales' visit on Tuesday - another team that has lost its opening two matches in Group G.
"The important thing is to keep calm," Hitzfeld said. "If we win our three matches at home and if we take some points in Cardiff and Sofia (against Bulgaria) then we can come back."
Central defender Steve von Bergen could miss facing Wales in Basel because of a knee injury, though Hitzfeld has bigger problems with his attack. Switzerland has only five goals in its last 12 matches, and none from its forwards.
After dismal World Cup campaigns, France and Italy have turned their fortunes around and top their respective groups after three qualifying matches.
France opened up group play with a 1-0 home loss to Belarus but has bounced back well with an away win at Bosnia-Herzegovina followed by Saturday's 2-0 victory over Romania. Laurent Blanc's team should easily beat bottom side Luxembourg in Metz in its fourth qualifier.
"The team spirit in the squad is a pleasure to see," said Alou Diarra, who captained France against Romania. "There is an enormous amount of talent in this squad. These two wins are good for our morale and now we're up and running in the qualifiers. Now it's got to be more of the same and three points against Luxembourg."
Blanc has no new injury worries but could make changes to freshen up his team, unlike Italy coach Cesare Prandelli, who was happy with his players' performances in the goalless draw at Northern Ireland on Friday.
It was the first time the Azzurri had dropped points in Euro 2012 qualifying but they are still a point clear of second-place Estonia, which beat Serbia away on Friday.
"I'm not thinking about changing a lot for the game with Serbia," Prandelli said. "Its loss at home to Estonia changes things as I would have preferred not to be facing a team with a point to prove."
Italy defender Leonardo Bonucci went for an x-ray after taking a heavy blow to his left foot against Northern Ireland, but scans revealed there was no break and he could feature against Serbia.
Also among Tuesday's 23 qualifying matches, Ireland is at Slovakia, Portugal is at Iceland and Greece hosts Israel.
