CINCINNATI (AP) -- Carlos Gonzalez tied his career high with three of Colorado's six homers, and Troy Tulowitzki went 5 for 5 with a pair of homers Wednesday night, powering the Rockies to a 12-4 victory over the Cincinnati Reds.
The Rockies hadn't hit six homers in a game since they had that many against the Marlins on July 4, 2008, according to STATS LLC.
Gonzalez got Colorado's splurge going with a solo shot and a three-run drive off Pedro Villarreal (0-1), who was roughed up by one of the NL's top offenses in his first big league start. Tulowitzki tied his career high with five hits, including a two-run homer and a solo shot.
Todd Helton also homered as the Rockies piled up a season-high 20 hits, the most allowed by Cincinnati since 2009. The Reds came in with the second-best earned run average in the NL.
Jon Garland (4-6) gave up four runs -- all in the first -- and lasted six innings.
The Rockies took the last two games of their series, ending a streak of six straight losses against Cincinnati. Colorado is 3-6 against the Reds over the last two seasons.
The Reds put Johnny Cueto on the 15-day disabled list before the game, the second time this season that their top starter has been sidelined by a strained muscle in the back of his shoulder. Cincinnati's top starter was out from April 15 to May 19 with the injury.
Villarreal was promoted instead of left-hander Tony Cingrani because it was his turn to start at Triple-A Louisville. Rockies manager Walt Weiss didn't change his lineup for the right-handed Villarreal, who lasted only 3 2-3 innings and allowed 10 hits and six runs.
Gonzalez hit his solo homer in the first. Tulowitzki had a two-run shot in the third, his second homer in two games. He also had a two-run homer in the eighth inning Tuesday for a 5-4 win.
Gonzalez's three-run homer in the fourth gave him 10 multihomer games in his career, including two this season. He added a two-run shot in the eighth off Manny Parra, leaving him with 17 homers. He also hit three in a game against Houston on May 30 last season.
Garland also had a rough time in the first inning, when Xavier Paul hit a three-run shot for a 4-1 lead. Garland is one of the NL's best at getting ground balls. After Paul's homer, he retired 13 of the next 17 batters on grounders or strikeouts.
Reds second baseman Brandon Phillips missed his fourth straight game with a bruised left forearm, which was hit by a pitch. He's expected back for a weekend series against first-place St. Louis.
NOTES: An MRI on Rockies starter Tyler Chatwood found nothing more than inflammation in his triceps. He's expected to miss one start. Chatwood had to leave his start on Monday in Cincinnati during the fifth inning because of soreness in the triceps. ... Rockies CF Dexter Fowler was sick and out of the starting lineup. ... Reds OF Chris Heisey plans to start a rehab assignment on Friday at Triple-A Louisville. Heisey has been on the disabled list since April 29 with a pulled right hamstring. ... Bengals players took batting practice before the game. They're holding supervised workouts this week.
