MILWAUKEE (AP) -- Kyle Lohse failed to find his rhythm against his former team.
The St. Louis Cardinals pounded out 11 hits against him in six innings on the way to a 6-1 victory.
"They just never gave me an opportunity to settle in. It was really a battle for me all night," Lohse said. "It wasn't my best night. I felt good starting out but then it just kind of got away from me. I wasn't getting my off-speed pitches over enough."
Brewers manager Ron Roenicke said the combination of Lohse not being as sharp as usual and the hot hitting of the Cardinals was too much to overcome.
"(Lohse) left some balls up in the zone," Roenicke said. "Those guys can really hit. They hit the off-speed well, they hit the fastballs well. They kill mistakes."
Lohse (1-3) pitched five innings, giving up 11 hits and four earned runs. He walked one and struck out three. His ERA climbed to 3.16 from 2.53.
The Brewers have scored just 13 runs in six starts this season for Lohse.
Shelby Miller held the Brewers to one run over six innings to beat Milwaukee for the second time this season. In his two starts against Milwaukee, Miller has limited the Brewers to just one run over 13 innings.
"I faced them the second game of the year so I knew what I needed to do and executed," the 22-year-old right-hander said. "My biggest focus in this game was keeping the ball down in the zone."
Matt Holliday and Carlos Beltran homered for the Cardinals, who have taken the first two of a four-game series.
"Miller did a real nice job making his curveball really effective," St. Louis manager Mike Matheny said. "He had a good break on his curveball and was throwing it in the zone for strikes and keeping them honest. He had late life on his fastball. He controlled counts, challenged them to put the ball in play and the guys made good plays behind him."
Miller (4-2) gave up seven hits and a walk in six innings while striking out five. He was scoreless through the first five innings before allowing a sacrifice fly by Jonathan Lucroy.
"Miller was really good again," Roenicke said. "Great fast ball. Threw the breaking ball for strikes. This is a good looking young pitcher."
Carlos Martinez, Seth Maness and Fernando Salas held the Brewers without a run over the final three innings. Martinez and Maness made their major league debuts.
"Carlos, he's shown what he can do and we knew he'd be excited for the opportunity," Matheny said. "There's a big upside for him. And Seth has proven he really knows how to work the plate and he's got command as good as any young player I've seen. If we get in a tight spot, we know he can throw quality strikes. It's a great compliment to our organization that the kids we're bringing in here don't look like they're overwhelmed."
The Cardinals jumped in front in the third inning on a two-out, two-run home run by Holliday off Lohse. Allen Craig followed with a single but was thrown out at the plate attempting to score on a double by Yadier Molina, one of three Cardinals thrown out at the plate.
St. Louis extended its lead in the fifth on Jon Jay's two-run double. Beltran added a solo home run leading off the seventh for the Cardinals, who scored another run in the inning on a passed ball. Allen Craig was thrown out at the plate attempting to score on a single by Pete Kozma to end the inning.
NOTES: Aramis Ramirez was reinstated from the 15-day disabled list on Friday and started at third base. He singled in the second inning in his first at-bat since April 5. The Brewers optioned infielder/outfielder Josh Prince to Triple-A Nashville. ... Brewers OF Carlos Gomez extended his hitting streak to 10 games with a second-inning single.
