PHOENIX (AP) -- Patrick Corbin allowed a run in the first inning, then did what he always seems to, shutting down the opponent the rest of the way.
Normally, that leads to a win for the Diamondbacks. Against Tyson Ross, it wasn't good enough.
Corbin pitched seven scoreless innings after giving up a run-scoring single to Carlos Quentin in the first but was outpitched by Ross, who threw eight dominant innings to lead the Padres to a 1-0 win in Sunday's series finale.
"Patrick threw a great game for us, but we didn't capitalize on our opportunity to keep the game going," Diamondbacks manager Kirk Gibson said.
Corbin (12-2) was sharp, allowing a run and six hits in eight innings, the 12th time in 21 starts he's allowed an earned run or fewer. Arizona's offense didn't give him any support, though, managing three hits against Ross and none against closer Huston Street in the ninth.
The Diamondbacks failed to take advantage of leadoff hits in the second and third innings and went 0 for 5 with runners in scoring position for their first 1-0 loss at Chase Field in nearly three years.
"I just want to do the same thing: Go up there and give up as few runs as I can," Corbin said. "Today, we didn't get many chances to score, and the opportunity we did have, we didn't capitalize on it."
Ross (2-4) had a lot to do with it. The right-hander had ended a 12-game losing streak -- dating to last season -- in his previous start, allowing a run in six innings against the Brewers.
And he was sharp against the Diamondbacks, repeatedly getting them to chase his slider or hit balls into the dirt. He gave up a leadoff single to Eric Chavez in the second inning and a leadoff triple to Pennington in the third but stranded both.
Ross didn't allow another hit until Pennington's one-out single in the eighth inning, and he was replaced in the ninth after throwing 101 pitches.
Behind Ross' gem, San Diego finished 6-4 to win its first road trip since Aug. 24-26 and its first of six or more games since June 25-July 4, 2012.
"I've always tried to blend pitches as best as possible, and some of the swings I got on sliders in the dirt on even counts, (it's) kind of tribute to that looking like a fastball coming out of the hand," Ross said.
Corbin has been one of baseball's best pitchers this season, entering Sunday's game fourth in the majors with an ERA of 2.41 and an 8-0 record at home. A first-time All-Star, the left-hander won his last start, allowing a run in six innings to beat the Cubs.
He was just as good in this one.
He got two quick outs in the first inning, but Chase Headley followed with a triple and scored when Quentin followed with a single through the left side.
Corbin worked around a pair of base runners in the second inning, then settled into a groove, allowing just two more hits the rest of the way. He was lifted for a pinch hitter in the eighth inning after striking out eight and walking none.
"The first two innings, I felt like I was still getting loose," Corbin said. "After that, I felt comfortable, but Ross pitched a great game for them. He has good stuff, and today was his day."
NOTES: The Diamondbacks recalled RHP Chaz Roe from Triple-A Reno before the game to replace LHP Tyler Skaggs, who was sent down after allowing seven runs in 3 /3 innings Saturday night. ... Diamondbacks LF Jason Kubel was scratched from the lineup with a stiff back. ... RHP Ian Kennedy will try for the 10th straight start to win career game No. 50 when the Diamondbacks open a road series at Tampa Bay on Tuesday.
