MILWAUKEE -- Adam Wainwright's ankle injury put a damper on Mitch Harris' major league debut for St. Louis and took most of the luster off the Cardinals' 5-3 victory over the Milwaukee Brewers on Saturday night.
Wainwright was helped from the field by a trainer after injuring his left ankle while stumbling out of the batter's box on his popup to first leading off the fifth inning. He allowed three hits in four shutout innings.
"It's something in the back of my ankle so we'll see what it is on Monday," said Wainwright, who was wearing a walking boot after the game. "Everything right now is just all speculation."
Wainwright will be re-evaluated when the Cardinals return to St. Louis. The Cardinals complete a six-game trip with a Sunday afternoon game at Miller Park.
"It was by far the best I felt this year," Wainwright said. "I really had things working. I started changing arm angles a little bit, working in and out better than I have been and I just was having a lot of fun out there. It reminded me of last year a lot.
"Those strides I was talking about making over the course of the year, I started to make them today. That's the hardest part just knowing I was making such good adjustments, and now I've got a setback."
Harris then tossed 1 1/3 scoreless innings in his first big league game at the age of 29 after serving five years of active duty in the U.S. Navy following his graduation from the Naval Academy.
"It's one of those bittersweet ... the last thing I want to see happen to Adam, but I was happy to finally get in there," said Harris, who struck out the first batter he faced.
Matt Holliday hit a three-run drive in the seventh for St. Louis, which has won four in a row. It was Holliday's first homer of the season.
The Brewers lost for the 10th time in 11 games to fall to 3-15. Every other team in the majors has at least six victories.
Milwaukee scored three runs with two outs in the eighth on an RBI single by Adam Lind and a bases-loaded double by Aramis Ramirez, but Hector Gomez bounced out to third to strand the tying runs.
Matt Belisle (1-0) got five outs for the win and Seth Maness pitched 1 1/3 innings for his first save.
Holliday's 26th career homer against the Brewers put the Cardinals up 5-0. Matt Carpenter, who extended his hitting streak to 12 games with a fifth-inning single, doubled with one out in the seventh and Jason Heyward drew a walk.
Brewers manager Ron Roenicke was ejected by plate umpire Dale Scott during the pitching change to Jeremy Jeffress, whose first pitch was hammered over the wall in right-center by Holliday.
"I didn't like his strike zone, so I told him he had a bad night," Roenicke said. "They're calling what they see. Some nights it works out against you and unfortunately, with us, it seems like it's been against us. But we're not playing good baseball and it happens all the way around, where you don't get calls, you don't get breaks, and that's what we're going through."
St. Louis grabbed a 2-0 lead in the second when Kolten Wong had an RBI triple and came home on a wild relay throw to third by shortstop Jean Segura.
Milwaukee right-hander Wily Peralta (0-3) allowed seven hits in six innings in his third consecutive loss. He struck out four and walked two.
