The Eredivisie leaders travel to the GN Bouw Stadion full of confidence having suffered only one league defeat this season, but Marcellis is taking nothing for granted against the mid-table Eerste Divisie side. He told VoetbalPrimeur: "We owe it to ourselves to go there and win, but it is not a formality. We will approach the game very seriously because we want to go far in the cup. It is important that we stand Thursday. "We must be sharp, otherwise we could make it unnecessarily difficult for ourselves." Also on Thursday, Eredivisie high-flyers Feyenoord visit Go Ahead Eagles and NEC Nijmegen host FC Volendam. Teenager Jetro Willems could be handed his first PSV Eindhoven start on Wednesday when Fred Rutten's side welcome Lisse to the Philips Stadion. Willems made his senior debut for the club as a second-half replacement for the injured Abel Tamata in Sunday's 1-1 Eredivisie draw at Vitesse Arnhem. The 17-year-old told the Eindhovens Dagblad newspaper: "At first I was a little nervous, then I think I did pretty well. If the team needs me in the next few games, I will be there." League champions Ajax - last year's cup runners-up - contest one of Wednesday's two all-Eredivisie encounters when they travel to the Parkstad Limburg Stadion to play Roda JC. Jasper Cillessen will be in goal for the Amsterdammers with Kenneth Vermeer suspended following his red card in Sunday's 1-1 draw against Feyenoord, while coach Frank de Boer also has a doubt over forward Miralem Sulejmani due to a groin injury. Vitesse face ADO Den Haag at the Gelredome in the other all-top-flight tie. Also on Wednesday, cup holders FC Twente take on SC Genemuiden, De Graafschap visit De Treffers, Heracles Almelo play Berkum and Sparta Rotterdam face Sparta Nijkerk. The cup action kicks off on Tuesday, when Eredivisie basement boys Excelsior will look to put their league worries aside for the visit of GVVV Veenendaal. RKC Waalwijk will look to bounce back from Saturday's 4-1 league hammering at VVV-Venlo when they travel to FC Zwolle, while Heerenveen - 4-1 winners at FC Utrecht at the weekend - take on Harkemase Boys. Also on Tuesday, Achilles 29 face MVV, Almere City FC tackle Eindhoven and TOP Oss meet FC Den Bosch.
