Angel di Maria will miss Manchester United's crunch match against Liverpool on Sunday.
United's record signing has missed the last two games with a hamstring injury and will not be in the match day squad this weekend, manager Louis van Gaal confirmed at his pre-match press conference on Friday.
The good news for Van Gaal is that defenders Rafael and Phil Jones are both back from their long-term groin and shin injuries.
Having seen his first campaign interrupted by injuries, it is something of a relief for the Dutchman to see Jones and Rafael return. The duo have both been out for almost two months.
"Now, I have only four players injured, so that's better than ever I believe," the United manager said.
"Only (Luke) Shaw, (Chris) Smalling, Di Maria and (Daley) Blind (are out)."
