Fabiano is currently sidelined for around six weeks with a knee injury suffered in last weekend's defeat to Athletic Bilbao.
The 30-year-old enjoyed a hugely successful three-year spell at Sao Paulo earlier in his career, scoring 118 goals in 160 games before moving to Porto in 2004.
After a short spell in Portugal, the forward moved to Sevilla, where he scored 106 goals in all competitions and helped the Andalusian club win six trophies, including two UEFA Cup and two Copa del Rey crowns.
In August Luis Fabiano, after months of transfer speculation linking him with a move away, signed a two-year contact extension with Sevilla tying him to the club until 2013.
This season the former Ponte Preta and Rennes hitman has not been an automatic starter for Sevilla, but remains their joint-leading scorer in La Liga with 10 goals.
Luis Fabiano, who made financial sacrifices to help push through the move, said: "Money is not everything in life. Nothing could pay for how happy I am to once again be able to wear the shirt of the team closest to my heart.
"I owe everything I have to Sao Paulo. I'm going to sweat for this shirt and I'm going to score many goals. I'm already thinking about coming out of the dressing room tunnel at the Morumbi stadium."
Luis Fabiano is set to be presented by Sao Paulo on March 30.
