Midfielders James Dayton, David Silva and Danny Buijs are set to be included in the Kilmarnock squad after recovering from injury.
New signings Ben Gordon and Michael Nelson are available after being ineligible for the midweek William Hill Scottish Cup replay win over Dundee.
Defender Gary Fisher is a doubt with a foot problem, while goalkeeper Anssi Jaakkola, defenders Alex Pursehouse and Ryan O'Leary (all knee) remain out.
Iain Turner is set to be restored in goal for Dunfermline, but new signing Mark Kerr's involvement depends on the Pars receiving international clearance in time.
Turner, who is on loan from Preston, was ineligible for the William Hill Scottish Cup replay loss to Inverness on Wednesday night, when replacement Chris Smith was among those culpable for one of the visitors' goals.
Kerr could make his Pars debut after signing until the end of the season, but midfielder Paul Burns (dead leg) is likely to miss out again and Craig Easton, Austin McCann, Nick Phinn, Steven Bell and Paul Gallacher are absent.
Kilmarnock (from): Bell, Fowler, Pascali, Sissoko, Shiels, Silva, Dayton, Racchi, Kelly, Kroca, Hay, Heffernan, Gros, Kennedy, Letheren, McKeown, Davidson, Johnston, Fisher, Buijs, Gordon, Nelson, Harkins.
Dunfermline (from): Turner, Smith, Boyle, Keddie, Dowie, Potter, Graham, Cardle, Thomson, Kirk, Willis, Buchanan, Barrowman, Mason, Hardie, Byrne, Young, Rutkiewicz, McDougall, Burns, Kerr.