Substitute midfielder Giuliano scored in the second half to give Internacional a 1-0 win over fellow Brazilian side Sao Paulo in the first leg of the Copa Libertadores semifinals Wednesday.
Giuliano sent the ball off the inside of the post following build up play by Andres D'Alessandro and Alecsandro in the 68th minute, three minutes after taking the field.
The return leg will be played in Sao Paulo's Morumbi stadium next Thursday.
Mexico's Guadalajara was held to a 1-1 draw at home against Universidad de Chile on Tuesday in the other semifinal first leg.
The Copa Libertadores is the top club competition in Latin America. The tournament took a break after the quarterfinals to make way for the World Cup, restarting at the semifinal stage.
Inter won the Copa Libertadores in 2006, while Sao Paulo was champion in 1992, 1993 and 2005.
The semifinal between the teams is a repeat of the 2006 final, which Inter won.
Inter had the best chances at home in the Beira-Rio stadium, with Andres D'Alessandro curling a free kick wide from 25 yards (meters) in the 19th minute and winger Taison's header forcing a diving save from goalkeeper Rogerio Ceni in the 29th.
Ceni pushed Andrezinho's shot from the edge of the area round the post in the 47th minute as Inter increased the pressure in the second half.
After Giuliano opened the scoring, defender Kleber had a chance to extend the lead, but shot over from close range in the 73rd minute.
Sao Paulo had few chances, with Dagoberto's deflected shot flying wide in the 57th minute and Hernanes shooting at Inter goalkeeper Renan in stoppage time.
