It was the highest scoring game in McNeese State history, surpassing Sam Houston State's 52-47 victory over the Cowboys in 2004.
Pendland averaged 8.6 yards a carry and McNeese State averaged 10 yards a carry as a team as the Cowboys (7-2, 4-1 Southland Conference) rushed for 418 yards.
Derrick Fourroux added 118 yards rushing and tied the school record for combined touchdowns with 90, rushing for one and throwing for another. He was 8-for-16 for 190 yards.
McNeese State led 28-14 at halftime and the teams exchanged touchdowns in the third quarter before the Cowboys took command with 21 fourth-quarter points.
Blake Joseph led the Bearkats (4-5, 2-3) with 300 yards passing and four touchdowns.