Romo was limited to just four games in 2015 after breaking his collarbone on two separate occasions, and the Cowboys ended up going 1-11 in the games he was sidelined. Dallas has reached the playoffs just four times in Romo's 10 years as the team's starting quarterback, and there's no question he'd like to lead the team to glory just once before his days under center are finished.
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Adrian Peterson, Minnesota Vikings
After missing all but one game in 2014 due to a suspension, Peterson bounced back in a big way last season. He led the league in rushing yards for the third time in his career, which helped the Vikings to an 11-5 record and a first-place finish in their division. Peterson is one of the best running backs of his generation; the 2,097 yards he ran for in 2012 placed him second on the single-season all-time list.
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Philip Rivers, San Diego Chargers
Rivers has been to five Pro Bowls and has never missed a game in 10 seasons as the starting quarterback in San Diego, but the team hasn't had much success during his time under center. The Chargers have largely hovered around .500, finishing within a game of the mark either way in six of the past eight seasons. And 2016 will be especially important for Rivers, who's looking to improve on a 4-12 campaign from a year ago that saw him throw the ball a league-leading (and career-high) 661 times.
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Jimmy Graham, Seattle Seahawks
Graham made a name for himself as Drew Brees' main target for five seasons in New Orleans, but the Saints' lone Super Bowl victory came in 2009, which was the year before Graham arrived. After being traded to the Seahawks, his production was down significantly last season, and he was limited to appearing in just 11 games due to injury. He's still not completely recovered, and may even miss Week 1. But the Seahawks have enough talent on both sides of the ball to get Graham where he needs to go -- if he can get back to producing like he did for the Saints.
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Julius Peppers, Green Bay Packers
Peppers might be headed to the Hall of Fame one day as one of the greatest defensive players of his time, and all that's missing from his résumé is a victory in the Super Bowl. He finished with 10.5 sacks last season, and with six more in 2016 he'll move into fifth on the all-time list. Peppers appeared in one Super Bowl in 2003 with the Panthers, and came within a game of returning while playing for the Bears in 2010. The Packers are expected to contend for the NFC crown, so this may be the year he gets another shot.
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Carson Palmer, Arizona Cardinals
Palmer, at 36 years old, is getting better with age. He threw for a career-best 4,671 yards and 35 touchdowns while leading the Cardinals to a 13-3 record last season, and came within one game of the Super Bowl before suffering defeat in the NFC title game at the hands of the Panthers. Arizona is expected to be just as formidable in 2016.
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J.J. Watt, Houston Texans
Watt has played only five NFL seasons, so there's plenty of time to get the ring that every player desires. But it has to be frustrating being so dominant defensively while the offense has struggled the past few years, and Houston will begin 2016 with a new starting quarterback for the fourth time in as many seasons. Watt has recorded 20.5 sacks twice in his career, and led the league in that category with 17.5 last season.