2006: French Open quarterfinals (Nadal wins 6-4, 6-4 Ret.)
In the pair's first meeting, Djokovic retires and Nadal gets the win. But the Serb's French Open quarterfinal appearance propels him up the rankings.
Forget Federer — this is the marquee rivalry in tennis. The 2013 US Open final marked the 37th time Rafael Nadal and Novak Djokovic have played each other, a record in the Open Era. Nadal leads the overall series 22-15 and is currently enjoying perhaps his best year ever, but Djokovic hasn't been without his moments over the years. Take a look back at some of their most memorable matches.
2013: US Open final (Nadal wins 6-2, 3-6, 6-4, 6-1)
Nadal parlayed the strong hard-court results into his second career title in Flushing Meadows, squashing a Djokovic rally in the middle sets. It was the Spaniard's 13th career Grand Slam triumph.
2013: Montreal semifinal (Nadal wins 6-4, 3-6, 7-6(2))
Nadal scored his first hard-court victory over Djokovic since 2010 and sent a strong message just ahead of the US Open with the three-set victory. Nadal went on to win the tournament for his ninth title of the year.
2013: French Open semifinal (Nadal wins 6-4, 3-6, 6-1, 6-7(3), 9-7)
In a match as stirring as the score line indicates, Nadal had to come back from a break down in the fifth set to continue his winning ways at Roland Garros. He would beat countryman David Ferrer two days later to win his record eighth French Open title.
2013: Monte Carlo final (Djokovic wins 6-2, 7-6(1))
Djokovic stunned Nadal on the Spaniard's beloved clay just a month ahead of the French Open with a relatively easy straight-sets win, serving notice that he would be a contender at Roland Garros. It was Djokovic's third career win over Nadal on the red dirt.
2012: French Open final (Nadal wins 6-4, 6-3, 2-6, 7-5)
Nadal and Djokovic battled in a two-day, rain-plagued final at Roland Garros. Nadal earned the victory and a record seventh French Open title.
2012: Italian Open final (Nadal wins 7-5, 6-3)
Rafael Nadal continued his dominance on the red clay to take his sixth Italian Open title in Rome. Nadal also regained some momentum in his rivalry with Djokovic winning their last two meetings.
2012: Monte Carlo final (Nadal wins 6-3, 6-1)
Rafael Nadal picked up a big win over Novak Djokovic at the 2012 Monte Carlo Masters tournament in Monaco. Not only was the victory Nadal's eighth straight Monte Carlo title, but it also ended his string of seven consecutive losses to Djokovic in title matches. It also improved Nadal's all-time record against his rival. Nadal's edge vs. Djokovic is now 17-14.
2012: Australian Open final (Djokovic wins 5-7, 6-4, 6-2, 6-7(5), 7-5)
Djokovic outlasted Nadal in this five-set thriller that took five hours and 53 minutes to play, making it the longest Grand Slam final match ever. This was Djokovic's third time winning the Australian Open.
Getty ImagesQuinn Rooney
2011: US Open final (Djokovic wins 6-2, 6-4, 6-7, 6-1)
Rafael Nadal lost to Novak Djokovic for the sixth time this year. He never won a match against the No. 1-ranked player in 2011.
Getty ImagesMatthew Stockman
2011: Wimbledon final (Djokovic wins 6-4, 6-1, 1-6, 6-3)
Novak Djokovic defeated Rafael Nadal for the fifth time in 2011 to win the Wimbledon title. Djokovic also claimed the No. 1 ranking, bumping Nadal to No. 2.
AFP/Getty ImagesGLYN KIRK
2011: Rome final (Djokovic wins 6-4, 6-4)
Djokovic enjoys some time with the trophy after beating Nadal in the men's final in Rome and running his record for the season to 37-0.
AFP/Getty ImagesANDREAS SOLARO
2011: Miami final (Djokovic wins 4-6, 6-3, 7-6(4))
Djokovic rallies from a set down in Florida to defeat Nadal for the second straight tournament.
Getty ImagesMike Ehrmann
2011 Indian Wells final (Djokovic wins 4-6, 6-3, 6-2)
Nadal snagged the first set in the desert, but Djokovic was just too much for the Spaniard, easily winning the next two.
2010 US Open final (Nadal wins 6-4, 5-7, 6-4, 6-2)
Nadal needed four sets to dispatch the Serb and earn his third Slam title of 2010.
2009 Madrid semifinal (Nadal wins 3-6, 7-6(5), 7-6(9))
Djokovic did not go down easily in Madrid, winning the first set and forcing Nadal into two set tiebreakers.