Nikica Jelavic - who was the subject of a failed bid from West Ham this week - will miss the game with a sickness bug.
New midfield signing Mervan Celik could be named in the squad for the first time, while Kirk Broadfoot, Steven Naismith, Kyle Lafferty, Jamie Ness and Steven Whittaker remain on the sidelines.
Hibernian will be without Leigh Griffiths and Garry O'Connor.
Griffiths this week accepted a two-match ban after television footage appeared to show him making a one-fingered gesture during his side's 3-2 loss to St Johnstone last weekend, while O'Connor serves a one-match suspension for reaching six yellow cards.
New signings James McPake and Tom Soares are both included in Pat Fenlon's squad for the trip but Ian Murray and Danny Galbraith both remain sidelined with groin injuries.
Rangers (from): McGregor, Papac, Bocanegra, Wallace, Kerkar, Goian, Bartley, Davis, Aluko, Edu, Healy, Wylde, McCulloch, Ortiz, Alexander, Bedoya, McCabe, Celik.
Hibernian (from): Stack, Hart, Francomb, Towell, Hanlon, Stephens, Booth, Sproule, Wotherspoon, Stevenson, Soares, McPake, Scott, Osbourne, Welsh, Brown, Doyle, Stanton, Smith.