Lyon to play Bayern Munich in Women's Champions League
Lyon, which will play the first leg at home in March, has won its four games so far by a combined score of 27-0, with forward Ada Hegerberg scoring nine of the goals.
Glasgow City, the only independent women's club left in the draw, was paired with Wolfsburg. The German club's back-to-back European titles in 2013 and '14 are the only times Lyon did not win in the past eight seasons.
The quarterfinal matches will be played on March 24-25 and April 1-2.
In the semifinals, Lyon or Bayern will face Arsenal or PSG, while either Glasgow or Wolfsburg will take on Atlético or Barcelona.
The final is set for May 24 in Vienna, Austria.