Inverness manager Terry Butcher could keep faith with a winning line-up.
Caley Thistle lined up with an unaccustomed back four of Steve Williams, Josh Meekings, David Proctor and Kenny Gillet against Hearts but emerged 1-0 winners to stand two points adrift of a top-six place.
Butcher's injury problems have eased slightly with Aaron Doran back in training after a shoulder injury, while the club have brought in striker Sam Winnall on loan from Wolves until the end of the season. Defender Roman Golobart (ankle) and midfielder Andrew Shinnie (foot) remain sidelined.
St Mirren midfielder Kenny McLean will miss the trip to the Highlands after breaking his collarbone.
The Scotland Under-21 cap sustained the injury in a training collision on Thursday.
Skipper Jim Goodwin, who has signed a new contract at the Paisley club which keeps him at the club until at least the summer of 2014, remains on the sidelines with a calf strain.
Inverness (from): Tuffey, Piermayr, Tokely, Williams, Gillet, Proctor, Hayes, Tansey, Foran, Tade, G Shinnie, McKay, Ross, Esson, Meekings, Morrison, Sutherland, Winnall.
St Mirren (from): Samson, van Zanten, McAusland, Mair, Tesselaar, Barron, Mooy, Carey, Teale, McGowan, Imrie, Thompson, Smith, Thomson, Murray, Hasselbaink, Reilly, Naismith.