Demba Ba is likely to return up front after being ineligible for the Europa League, with Fernando Torres set to make way after playing against Basel.
Eden Hazard is in line to face the Swans again after being sent off for kicking a ball boy during February's Capital One Cup semi-final between the teams.
Gary Cahill was an unused substitute in the win in Switzerland and could start in defence following his six-week absence with a knee injury, with Oriol Romeu (knee) the only definite absentee.
Swansea manager Michael Laudrup has no new injury concerns ahead of the meeting at Stamford Bridge.
Neil Taylor was an unused substitute against Southampton last weekend following a lengthy injury lay-off and Laudrup may decide to bring him back into the side.
The Dane will consider freshening up his line-up following a disappointing run of results and have the likes of Wayne Routledge and Ki Sung-yueng pushing for starts.