After Sir Alex Ferguson endured a "nightmare" Monday, when both Anders Lindegaard and David de Gea were ruled out, Amos was thrust into the spotlight for Tuesday night's Premier League win over Stoke.
Now attention turns to the weekend when, after joining Manchester City at the top of the Premier League, United must try and stay there by beating Chelsea on their own ground in a top flight game for the first time since 2002.
Although Ferguson did not offer an update on Lindegaard or De Gea, neither man was included in a list of those who have a chance of being fit for the weekend, which means Amos may be plunged into the biggest game of his life.
"I have been waiting a long time for an opportunity this season and thankfully it has come," said the 21-year-old.
"I feel I am ready to play at this level and it has been kind of frustrating that these chances don't come around.
"But you have to be ready when something like that happens and you are thrown straight in and I like to think I made the most of it."
In truth, Amos didn't have much to do.
The only time he was tested was due to a Cameron Jerome header, which he smothered at the second attempt.
However, the fact he didn't force himself into the action was a good sign as, just as a striker may snatch at chances because he knows they must be taken, so goalkeepers can underperform by trying to create work when there is none.
"In a sense I wanted more to do but then there is a temptation to go and chase things," he said.
"You see a lot of keepers with not much experience who try and make an impact, which there is no need to do. That is what I had in my head and I think I got that right.
"Obviously I wanted to be positive with any decisions."
An outfield player in his youth, Amos only became a goalkeeper at his local Bollington club in Macclesfield because his junior team were short of players one day and he was the tallest option.
Amos went on to Crewe, before joining United's academy.
After spending half a season on loan at Oldham last year, it was anticipated Amos would spend more time away from Old Trafford this year.
Instead, Amos has remained at Old Trafford and featured in all three Carling Cup matches earlier this season.
"All I can do is keep a clean sheet and play the best I can when I get a chance," said Amos.
"You have to do the best you can.
"It is the manager who makes the decisions and all I can do is put pressure on the other two any chance I get."
Such was the scrutiny De Gea would have been under following his below-par weekend display at Liverpool that the Spaniard's absence on Tuesday night may have been a blessing in disguise.
De Gea's presence in the directors' box does suggest he will not be absent for too long.
And, with Wayne Rooney (ankle), Nani (foot) and Ashley Young (hip) all said by Ferguson to have a chance of being available this weekend, United may be in a position to capitalise on the pressure they have been able to exert on Manchester City thanks to the contribution of old-boy Darron Gibson for Everton.
"Part of the plan," said Ferguson, with a beaming smile.
"It was a nice boost. All the lads are really pleased for Darron.
"It will be March time before all will be revealed in the league but we are on City's coat-tails and we aim to keep it that way."
