Columbus (United States) vs. Real Salt Lake (United States), 8 p.m.
Cruz Azul (Mexico) vs. Santos Laguna (Mexico), 10 p.m.
Toluca (Mexico) vs. Monterrey (Mexico), 8 p.m.
Saprissa (Costa Rica) vs. Olimpia (Honduras), 8 p.m.
Santos Laguna (Mexico) vs. Cruz Azul (Mexico), 8 p.m.
Real Salt Lake (United States) vs. Columbus Crew (United States), 10 p.m.
Monterrey (Mexico) vs. Toluca (Mexico), 8 p.m.
Olimpia (Honduras) vs. Saprissa (Costa Rica), 8 p.m.
Monterrey-Toluca winner vs. Santos-Cruz Azul winner
Real Salt Lake-Columbus winner vs. Olimpia-Saprissa winner
Olimpia-Saprissa winner vs. Salt Lake-Columbus winner
Santos-Cruz Azul winner vs. Monterrey-Toluca winner
Santos-Cruz Azul-Monterrey-Toluca winner vs. Olimpia-Saprissa-Real Salt Lake-Columbus winner
Olimpia-Saprissa-Real Salt Lake-Columbus winner vs. Santos-Cruz Azul-Monterrey-Toluca winner