ABU DHABI, United Arab Emirates (AP) West Indies were left reeling at 171-4 as Pakistan pressed for victory on the fourth day of the second test after setting up a stiff target of 456 runs.
Leg-spinner Yasir Shah took 2-60 while seamer Rahat Ali got the prized wicket of Darren Bravo for just 13.
Left-arm spinner Mohammad Nawaz then went for a successful lbw television referral against half century-maker Kraigg Brathwaite (67) to leave West Indies with a gigantic task to save the test on the last day.
West Indies already trails 1-0 in the three-match series after losing the first day-night test by 56 runs where Bravo hit a resilient century in the second innings.
Earlier, Pakistan stretched its lead to 455 before declaring their second innings at 227-2 at lunch.
Asad Shafiq scored successive half century with a fluent unbeaten 58 and West Indies' lone success came when Azhar Ali (79) chased a wide delivery of Miguel Cummins and was caught in the slips.
