Michael Williams scored 15 of his 17 points in the second half to lead San Francisco to a 78-63 win over Pepperdine on Saturday.
Perris Blackwell added 15 points and Cole Dickerson had 12 for the Dons (12-8, 2-4 West Coast), which got its second straight conference win.
Pepperdine's Jordan Baker scored a game-high 26 points but couldn't prevent the fifth straight loss for the Waves (7-10, 1-5). Pepperdine's last victory was at home against San Francisco on Dec. 29.
With the San Francisco 49ers' playoff game taking place nearby, a sparse crowd was on hand at War Memorial Gym.
Following a 3-pointer by Dickerson, San Francisco held a 32-26 lead at the half. The Dons used a 10-2 run after the break to extend their lead to 10 points with 7:55 remaining, and their 15-point margin of victory matched their largest lead.