Nick Hendra hit a go-ahead 3-pointer and Vlad Moldoveanu scored 26 points off the bench as American upset DePaul 62-57 on Wednesday night.
Hendra's shot from beyond the arc put the Eagles (2-8) up 59-57 with 2:28 remaining. After Will Walker missed a 3-point attempt for DePaul (6-4), Daniel Munoz was fouled and made a pair of free throws to put American up 61-57 with 34.4 seconds left.
Hendra finished with 17 points on 6-of-10 shooting.
Devin Hill scored 14 points and Walker added 13 for the Blue Demons, who played without center Mac Koshwal for the seventh straight game because of a left foot injury.
Moldoveanu scored seven points during a 9-2 run by American in the second half. His jumper gave the Eagles a 55-50 lead with 4:32 remaining.
DePaul trailed by 10 early in the second half but got back in the game with a 11-0 run keyed by Hill's seven points during the span. Hill's free throw gave DePaul a 35-34 lead.
Leading 18-17 in the first half, American scored nine straight points. Hendra made a 3-pointer, and Moldoveanu connected on a jumper to give the Eagles a 27-17 lead with six minutes remaining in the half.
Mike Bizoukas' layup cut the American lead to 32-24 with four seconds to play before halftime.
During the first half, the Eagles were 5 of 11 from 3-point range and held DePaul to 35.7-percent shooting.