The Ghanaian football association says midfielder Michael Essien has been ruled out of the World Cup with a right knee injury.
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The Chelsea player picked up the injury in January while at the Africa Cup of Nations in Angola.
The association says that "an evaluation by a combined team of medical experts from the Ghana Football Association and Chelsea Football Club revealed that Essien will not make full recovery until the end of July."
Ghana's World Cup campaign opens against Serbia on June 13.