Capitals beat Stanley Cup champion Blues 3-2 in OT in opener
Vrana beat Jordan Binnington with a wrist shot to the upper corner for his first point in five career games against the Blues.
Sammy Blais and Alex Pietrangelo scored for the Blues, and Binnington made 31 saves.
The Blues raised their Stanley Cup banner during a pregame ceremony that featured a video of members of the team celebrating with the cup during the offseason and highlights of the postseason run.
Matthews gave Toronto a 3-2 lead at 8:02 of the second and made it 4-2 on a power play with 5:10 left in the period. He has nine goals and two assists in the four season-opening games, starting with a four-goal game against the Senators in his NHL debut in 2016.
Scott Sabourin scored in his NHL debut for Ottawa, Brady Tkachuk, and Bobby Ryan added goals, and Craig Anderson made 37 saves. Former Toronto assistant D.J. Smith made his debut as an NHL head coach.
Fleury, now in his 16th season, improved to 10-5-0 in openers. The victory tied him with Curtis Joseph (10-2-0) and Martin Brodeur (10-5-3) for the most season-opening wins in NHL history.
Vegas, which will play in San Jose on Friday, improved to 6-1-2 all-time against the Sharks in the regular season.
Marcus Sorensen scored for San Jose. Martin Jones made 31 saves.
McDavid broke a 2-all deadlock with 5½ minutes to play, splitting the defense before beating goalie Jacob Markstrom on a strong solo effort.
Alexander Edler and Tanner Pearson had the goals for the Canucks, who won their previous five openers.
- Edmonton Oilers
- Toronto Maple Leafs
- Vegas Golden Knights
- Washington Capitals