The sixth week of the 2016 NFL season will kick off Thursday night with an AFC West matchup between the Denver Broncos and San Diego Chargers.
The Broncos are 4–1, while the Chargers are 1–4. San Diego will look to turn its season around at home against the defending Super Bowl champions, who will turn to second–year quarterback Trevor Siemian.
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The former Northwestern quarterback led the team to a 4–0 start before sitting out Week 5 due to a shoulder injury. Siemian has a 99.6 passer rating this season, with 824 yards, six touchdowns and three interceptions.
Siemian, who was a seventh round pick in 2015, will make his fifth NFL start on Thursday night.