Rex Ryan has a brash message for the Patriots following Bills victory

Buffalo Bills head coach Rex Ryan was flying high after the Bills got their first win of the season, stunning the Cardinals 33-18 in impressive fashion Sunday.

Next up for Buffalo is Ryan’s old nemesis — the undefeated New England Patriots. Ryan apparently doesn’t have much sympathy for New England’s current situation, with Tom Brady still serving his suspension and Jimmy Garoppolo out with a shoulder injury.

Fresh off Sunday’s win, Ryan had a message for the Patriots and Bill Belichick.

"Look, I can sit back and say I don’t care who plays quarterback because I know Brady ain’t," Ryan said. "I don’t care who plays quarterback. (Former Patriots quarterback) Steve Grogan can play quarterback.

"If Belichick’s playing quarterback, we’re coming after him."

The Patriots had no problems with the Texans on Thursday despite starting Jacoby Brissett. With the extra time to prepare, Belichick will be ready for this anticipated matchup.