49ers RB Brandon Jacobs inactive against Bills

Running back Brandon Jacobs’ debut with the San Francisco 49ers

will have to wait at least another week.

Jacobs is among those inactive for San Francisco against the

Buffalo Bills on Sunday. The big, burly former New York Giants

running back has not played since injuring his left knee in the

preseason. He practiced this week without limitations and had

declared himself healthy enough to play.

Rookies LaMichael James and A.J. Jenkins also were inactive for

the 49ers.

The Bills got a boost with safety Jairus Byrd (hip) and wide

receiver Ruvell Martin (ankle) on the active roster. Both were

listed as questionable earlier in the week. Martin also plays on

special teams.