Louisville quarterback Lamar Jackson looks for a receiver during the first quarter of an NCAA college football game against Florida State, Saturday, Sep. 17, 2016 in Louisville Ky. (AP Photo/Timothy D. Easley)
-Lamar Jackson, Louisville, ran for four TDs and threw for another score as the No. 10 Cardinals poured it on for a 63-20 victory over No. 2 Florida State.
-Mitch Trubisky, North Carolina, threw for a career-high 432 yards and three TDs to help the Tar Heels beat James Madison 56-28.
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-Cooper Rush, Central Michigan, threw six TD passes and for 352 yards in a 44-21 win over UNLV.
-Jimmy Seewald, Valparaiso, tied a school record with five TD passes and threw for 345 yards in his first start in a 49-24 win over Trinity International.
-Jake Melville, Colgate, threw for 315 yards and a career-high five TDs in a 55-13 win over Yale.
-Jerod Evans, Virginia Tech, tied a school record with five TDs in a 49-0 win over Boston College.
-Marcus Bagley, St. Francis, ran for a career-high 220 yards in a 13-9 victory against Columbia.
-Kyle Moreno, Brown, threw for three TDs and ran for two more in a 35-27 win over Bryant.
-I'Tavius Mathers, Middle Tennessee, scored four TDs and became the first player in school history to eclipse 100 yards rushing (157) and receiving (103) in a 41-21 win over Bowling Green.
-Brad Kaaya, Miami, threw for 368 yards and three TDs, helping the No. 25 Hurricanes roll to a 45-10 win Saturday over Appalachian State.
With the biggest win in school history less than 3 yards away, North Dakota State went for two and failed.
The Bison earned the ball back though – and they finished off the program's signature victory by running the ball right at Iowa.
Cam Pedersen kicked a 37-yard field as time expired and North Dakota State, of the FCS, rallied to beat No. 13 Iowa 23-21 on Saturday for its sixth straight win over an FBS opponent.
The loss was just the fourth by a ranked FBS team to an FCS school. North Dakota State isn't just another Football Championship Subdivision team, though. The Bison have won the last five FCS national titles.
12-Minutes the third and quarters were shortened to with No. 5 Clemson blowing out South Carolina State. The Tigers won 59-0.
18-Straight passes completed by North Carolina's Mitch Trubisky, breaking a school record that stood since 1967.
39-Straight road losses by Kansas after losing 43-7 to Memphis.
TWO TDS, NO TIME
How's this for quick scoring? Two touchdowns with no time off the clock.
That's what happened in the first quarter for No. 5 Clemson against South Carolina State.
After Wayne Gallman ran 3 yards for a score, the ensuing kickoff went to Ahmaad Harris in the end zone. The receiver flipped the ball to the official before taking a knee. That's a fumble! Clemson's Denzel Johnson pounced on the ball for the touchdown.
A week ago against Troy, Clemson was guilty of a special teams gaffe. Ray-Ray McCloud's 75-yard punt return ended when the receiver let go of the ball at the 1 before reaching the end zone.
Compiled by AP College Football Writer John Marshall.