San Diego State vs. Wyoming Prediction, Odds, Picks - November 1, 2025

Updated Nov. 1, 2025 3:04 p.m. ET

FOX Sports

The San Diego State Aztecs (6-1) are 10.5-point favorites when they host the Wyoming Cowboys (4-4) in an MWC matchup on Saturday, November 1, 2025 at Snapdragon Stadium. The point total is set at 42.5.

Against the Fresno State Bulldogs in their last contest, the Aztecs won 23-0. The Cowboys won versus the Colorado State Rams in their most recent game, 28-0.

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San Diego State vs. Wyoming Game Information & Odds

When: Saturday, November 1, 2025 at 7 p.m. ET
Location: Snapdragon Stadium in San Diego, California
TV: CBS Sports Network
Live Box Score on FOX Sports

San Diego State vs Wyoming Betting Information updated as of November 1, 2025, 2:45 p.m. ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
San Diego State	-10.5 (-111)	-439	+335	42.5	-109	-111

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San Diego State vs. Wyoming Prediction

Pick ATS: San Diego State (-10.5)
Pick OU: Under (42.5)
Prediction: San Diego State 29, Wyoming 12

Predictions are made by the Data Skrive betting model.

Learn more about the San Diego State Aztecs vs. the Wyoming Cowboys game on FOX Sports!

San Diego State vs. Wyoming Betting Insights

Based on the spread and over/under, the implied score for the game is Aztecs 26, Cowboys 16.
The Aztecs have an 81.4% chance to win this game per the moneyline's implied probability. The Cowboys hold a 23.0% implied probability.
San Diego State is 6-1-0 ATS this season.
Wyoming is 5-3-0 ATS this year.

San Diego State vs. Wyoming: 2025 Stats Comparison

	San Diego State	Wyoming
Off. Points per Game (Rank)	29.6 (80)	21 (112)
Def. Points per Game (Rank)	10.4 (2)	19.8 (38)
Turnovers Allowed (Rank)	4 (3)	12 (100)
Turnovers Forced (Rank)	8 (85)	11 (40)

San Diego State 2025 Key Players

Name	Position	Stats
Lucky Sutton	RB	657 YDS / 7 TD / 93.9 YPG / 5.3 YPC
Jayden Denegal	QB	1,224 YDS (64.8%) / 7 TD / 3 INT 88 RUSH YDS / 1 RUSH TD / 12.6 RUSH YPG
Jordan Napier	WR	41 REC / 570 YDS / 2 TD / 81.4 YPG
Christian Washington	RB	214 YDS / 2 TD / 30.6 YPG / 4.1 YPC 3 REC / 18 REC YDS / 1 REC TD / 6 REC YPG
Owen Chambliss	LB	42 TKL / 5 TFL / 2 SACK
Chris Johnson	DB	33 TKL / 2 TFL / 3 INT / 3 PD
Trey White	DL	23 TKL / 4 TFL / 4 SACK
Dalesean Staley	DB	28 TKL / 0 TFL / 1 INT / 1 PD

Wyoming 2025 Key Players

Name	Position	Stats
Kaden Anderson	QB	1,634 YDS (59.6%) / 11 TD / 6 INT
Chris Durr Jr.	WR	38 REC / 442 YDS / 4 TD / 55.3 YPG
Samuel Harris	RB	430 YDS / 1 TD / 53.8 YPG / 5.7 YPC 14 REC / 172 REC YDS / 0 REC TD / 24.6 REC YPG
Terron Kellman	RB	302 YDS / 4 TD / 37.8 YPG / 6 YPC 5 REC / 52 REC YDS / 0 REC TD / 10.4 REC YPG
Evan Eller	LB	40 TKL / 3 TFL / 2 SACK / 1 INT
Brayden Johnson	LB	37 TKL / 3 TFL / 1 SACK / 2 INT
Tyce Westland	DL	30 TKL / 4 TFL / 2 SACK
Desman Hearns	DB	24 TKL / 0 TFL / 2 INT / 2 PD