Louisville vs. Pittsburgh Prediction, Odds, Picks - October 14

Updated Oct. 14, 2023 3:06 p.m. ET

Data Skrive

The No. 14 Louisville Cardinals (6-0) visit the Pittsburgh Panthers (1-4) on Saturday, October 14, 2023 in a matchup between ACC rivals at Acrisure Stadium. Pittsburgh is a touchdown underdog. The game has a 44.5-point over/under.

The Cardinals won versus the Notre Dame Fighting Irish in their most recent game, 33-20. The Panthers' last contest was versus the Virginia Tech Hokies, and they lost by a score of 38-21.

Louisville vs. Pittsburgh Game Information & Odds

When: Saturday, October 14, 2023 at 6:30 PM ET
Location: Acrisure Stadium in Pittsburgh, Pennsylvania
TV: The CW
Live boxscore on FOX Sports

Louisville vs Pittsburgh Betting Information updated as of October 14, 2023, 2:46 PM ET.
Favorite	Spread (Odds)	Favorite Moneyline	Underdog Moneyline	Total	Over Moneyline	Under Moneyline
Louisville	-7 (-110)	-298	+238	44.5	-109	-111

Louisville vs. Pittsburgh Prediction

Pick ATS: Louisville (-7)
Pick OU: Over (44.5)
Prediction: Louisville 36, Pittsburgh 15

Learn more about the Louisville Cardinals vs. the Pittsburgh Panthers game on FOX Sports!

Louisville vs. Pittsburgh Betting Insights

Per the spread and over/under, the implied score for the game is Cardinals 26, Panthers 19.
The Cardinals have a 74.9% chance to collect the win in this contest per the moneyline's implied probability. The Panthers hold a 29.6% implied probability.
Louisville is 3-2-1 ATS this season.
Pittsburgh has covered just once in five matchups with a spread this year.

Louisville vs. Pittsburgh: 2023 Stats Comparison

	Louisville	Pittsburgh
Off. Points per Game (Rank)	36.3 (16)	23.4 (113)
Def. Points per Game (Rank)	17.7 (29)	26.0 (52)
Turnovers Allowed (Rank)	8 (64)	7 (47)
Turnovers Forced (Rank)	14 (5)	4 (121)

Louisville 2023 Key Players

Name	Position	Stats
Jawhar Jordan	RB	653 YDS / 8 TD / 108.8 YPG / 7.5 YPC 9 REC / 168 REC YDS / 1 REC TD / 28.0 REC YPG
Jack Plummer	QB	1,551 YDS (66.0%) / 12 TD / 6 INT 67 RUSH YDS / 1 RUSH TD / 11.2 RUSH YPG
Jamari Thrash	WR	30 REC / 519 YDS / 6 TD / 86.5 YPG
Ahmari Huggins-Bruce	WR	14 REC / 207 YDS / 2 TD / 34.5 YPG
Ashton Gillotte	DL	15 TKL / 5.0 TFL / 5.5 SACK
Devin Neal	DB	24 TKL / 0.0 TFL / 3 INT / 3 PD
TJ Quinn	LB	37 TKL / 0.0 TFL
Ramon Puryear	DL	12 TKL / 3.0 TFL / 2.0 SACK / 1 INT

Pittsburgh 2023 Key Players

Name	Position	Stats
Phil Jurkovec	QB	818 YDS (50.9%) / 6 TD / 3 INT 59 RUSH YDS / 1 RUSH TD / 11.8 RUSH YPG
Rodney Hammond	RB	196 YDS / 3 TD / 39.2 YPG / 4.3 YPC
Konata Mumpfield	WR	20 REC / 240 YDS / 2 TD / 48.0 YPG
Gavin Bartholomew	TE	12 REC / 258 YDS / 1 TD / 51.6 YPG
Bam Brima	DL	9 TKL / 3.0 TFL / 3.0 SACK
Shayne Simon	LB	16 TKL / 3.0 TFL / 2.0 SACK
Solomon DeShields	LB	17 TKL / 5.0 TFL / 1.0 SACK
Dayon Hayes	DL	12 TKL / 2.0 TFL / 2.0 SACK