This concludes a four-game home-and-home interleague series between the two teams. After the D-backs won the first game on Monday at Chase Field, the heavy-hitting Astros (74-46) have posted back-to-back wins, beating up the D-backs pitching staff for nine runs in each victory.
The Astros have amassed 29 hits in the two victories, with the damage distributed from the top of the lineup to the bottom. George Springer, Jose Altuve, Yuli Gurriel and Alex Bregman have four hits apiece over the last two games.
The D-backs (66-54) find themselves one game behind Colorado in National League wild-card positioning but still four games clear of their closest pursuer, Milwaukee, for the second spot. The last time they were as few as 12 games over .500 was June 10 (38-26).
The D-backs will have David Peralta back in the lineup following his reinstatement from the paternity list. Peralta's wife, Jordan, gave birth to Sofia on Monday, which happens to be David's birthday. The team optioned Anthony Banda to Reno to make room for Peralta on the active roster.
D-backs starting pitcher Patrick Corbin (9-11, 4.52 ERA)
Corbin, making his first career start against the Astros, is looking to reach double digits in victories for the second in his career. He finished 14-8 in 2013, then required Tommy John surgery the following spring.
He had perhaps his best outing of the season on Saturday against the Cubs, pitching 6 2/3 scoreless innings and limiting them to five hits and one walk while striking out eight. His slider was especially effective, resulting in 16 swinging strikes.
The D-backs are in desperate need for another quality outing. They've given up seven or more runs in five of their last seven games -- and they've lost all five.
Corbin has been a dramatically better pitching at home (7-3, 2.87) than on the road (2-8, 6.79). He's given up 16 home runs in 11 road starts, and opposing hitters have a .333 batting average and .622 slugging percentage against him in road games.
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Astros starting pitcher Mike Fiers (7-7, 4.36 ERA)
Fiers surrendered a season-high-tying six earned runs on five hits over four innings in a 6-4 loss to the Texas Rangers on Saturday. He paces the Astros in starts (23) and innings (128) and is tied for second with nine quality starts.
After a strong stretch in June and July (6-2, 2.36 ERA in 10 starts), Fiers in winless in his last four starts, going 0-3 with an 8.41 ERA and seven home runs allowed in 20 1/3 innings. He is 1-2 with a 4.50 ERA over four career starts against Arizona.
Fiers gives up 1.97 home runs per nine innings, seventh highest rate among starting pitchers with at least 100 innings. J.D. Martinez is 6 for 11 (.525) with two homers in his career against him, and Paul Goldschmidt is 4 for 11 (.364) with one homer. Both homered in Wednesday's loss at Minute Maid Park.