Isner falls in first round at Rosmalen

Seeded players struggle before rain at Rosmalen

John Isner was one of four seeded men's players to lose in the first round at the rain-interrupted Topshelf Open.

The third-seeded American lost 6-7 (3), 6-3, 6-4 to Evgeny Donskoy on Monday. No. 6 Marcos Baghdatis of Cyprus, No. 7 Victor Hanescu of Romania and No. 8 Daniel Gimeno-Traver of Spain were also upset.

Donskoy earned breaks against the big-serving Isner early in the second set and again in the final set to advance at the Wimbledon warm-up.

Carlos Berlocq beat Baghdatis 6-2, 6-4. Hanescu lost 6-4, 6-3 to Guillermo Garcia-Lopez, and Andrey Kuznetsov beat Gimeno-Traver 7-6 (4), 6-3.

Defending champion David Ferrer, the French Open runner-up, opens play Tuesday against Xavier Malisse.

In the women's event, second-seeded Dominika Cibulkova beat Lourdes Dominguez Lino 6-1, 6-7 (5), 7-6.

Third-seeded Carla Suarez Navarro advanced with a 6-3, 6-2 win over Johanna Larsson, and Lauren Davis of the United States defeated Andrea Hlavackova 6-3, 6-4.