The 2014 ACC player of the year tore his right medial collateral ligament in the 2015 opener, knocking him out for the remainder of the season. Two months later, he was diagnosed with Hodgkin lymphoma. Conner was declared cancer free in May and joined his teammates for the start of training camp. Conner rushed for 1,765 yards and scored 26 touchdowns for Pittsburgh in 2014. Conner joins a backfield that also includes Qadree Ollison, who rushed for 1,121 yards last season and was named the ACC offensive freshman of the year.
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GEORGIA RUNNING BACK NICK CHUBB
After rushing for 1,547 yards as a freshman in 2014, Chubb was on a similar pace last season until he tore the posterior cruciate ligament as well as two other ligaments in his left knee Oct. 10 at Tennessee. Chubb rushed for 747 yards and averaged 8.1 yards per carry but played in just six of the Bulldogs' 13 games. Chubb is working out with his teammates again and is hopeful he will be ready for the Sept. 3 opener with North Carolina. His return would boost a Georgia rushing attack that is missing Sony Michel, who ran for 1,161 yards last year but has a broken forearm that leaves his status for the start of the season uncertain.
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BYU QUARTERBACK TAYSON HILL
Injuries have wrecked Hill's last two seasons after he threw for 2,938 yards and ran for 1,344 yards in 2013. He played just four games in 2014 before a leg fracture and ligament tear knocked him out for the remainder of the season. Hill returned last year and suffered a season-ending foot injury in the Cougars' opener. Hill is back and has been named the starting quarterback after winning a preseason competition with Tanner Mangum, who set BYU freshman records for passing yards (3,377) and touchdown passes (23) last year.
Brendan Maloney-USA TODAY SportsBrendan Maloney
CLEMSON WIDE RECEIVER MIKE WILLIAMS
After catching 57 passes for 1,030 yards and six touchdowns in 2014, Williams played in just one game last year. Williams' season ended when he fractured his neck colliding with the goal-post padding as he made a 4-yard touchdown catch on Clemson's opening drive of the year. Williams now is back and should emerge as one of Heisman Trophy candidate Deshaun Watson's favorite targets this year for the second-ranked Tigers.
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NOTRE DAME QUARTERBACK MALIK ZAIRE
Zaire played brilliantly in a season-opening 38-3 rout of Texas last year but broke his ankle a week later against Virginia and missed the remainder of the season. DeShone Kizer replaced Zaire and threw for 2,884 yards with 21 touchdown passes and 10 touchdown runs. With Zaire healthy again and Kizer back as well, No. 10 Notre Dame has an uncertain quarterback situation as it heads into the season. Notre Dame coach Brian Kelly has said both Kizer and Zaire will play in the Sept. 4 season opener at Texas, though a starter hasn't been announced. Zaire isn't the only guy in the Notre Dame backfield returning from injury. Running back Tarean Folston also returns after tearing the anterior cruciate ligament in his right knee during last year's season opener.
Matt Cashore-USA TODAY SportsMatt Cashore
BAYLOR QUATERBACK SETH RUSSELL
Although he played in just seven games last season, Russell still threw for 2,104 yards and 29 touchdowns. Russell was gaining Heisman Trophy attention and had Baylor undefeated and in playoff position before he suffered a season-ending neck injury. He set a single-season school record by averaging 10.06 yards in total offense per play. Russell has been cleared to return and will try to lead a team reeling from off-field issues and adapting to interim coach Jim Grobe.