"And this one in the summer, although it was with Uruguay, although it didn't directly involve the Premier League, clearly it reflected on Liverpool as one of our great clubs.
"And it reflected on us.
"He's done his time here, but I can't say I'm sorry to see him go.
"I think it was good business on a number of levels from Liverpool to move Suarez on."
Suarez has appealed against his four-month FIFA ban to the Court of Arbitration for Sport, and will learn the outcome on Thursday.
The 78-cap striker was banned for 10 games for biting Chelsea's Branislav Ivanovic in 2013 and sidelined for seven matches for biting PSV Eindhoven's Otman Bakkal in Ajax action in 2010.
Scudamore said the Premier League does not need "every world mega star" to continue to flourish.
Former Ajax striker Suarez netted 31 league goals last term, his departure leaving a chasm for Reds manager Brendan Rogers to fill, but Scudamore rejected suggestions the Premier League cannot retain its top talents.
"We lost David Beckham as well, remember, we do often lose one or two," said Scudamore, talking at the Premier League season launch.
Referring to Real Madrid and Barcelona, he added: "The truth of the matter is the Spanish system producing those two very wealthy clubs, because of the way they sell their individual television rights, have always had the economic power.