Mirko Vucinic put the home team in front in the second minute with Andrea Pirlo and Claudio Marchisio adding further goals within the first half an hour.
Thomas Manfredini was then shown a red card for Atalanta, who were fortunate to avoid any further damage as Juve continued to attack but could not add to their first-half salvo.
Vucinic got the ball rolling with just 80 seconds on the clock when he showed his eye for goal by curling an effort inside the far post with only Andrea Consigli to beat.
Atalanta almost responded in the fourth minute but Gianluigi Buffon denied German Denis with his one and only intervention of the game.
Ten minutes later Pirlo made it two for the Bianconeri with a direct free-kick from 30 yards which he curled over the wall and into the top left-hand corner, beyond Consigli’s reach.
Five minutes later Giorgio Chiellini saw his shot from 20 yards deflected wide before Marchisio made it three in the 27th minute.
His 25-yard shot was curling away from Consigli, who got a hand to the ball but could not keep it out.
Five minutes later Atalanta’s hopes were well and truly dashed when Manfredini received a second yellow card for an unnecessary foul on Chiellini deep in the Juventus half.
Juventus had no intention of showing any mercy in the second half with Fabio Quagliarella’s effort ruled out for offside when he pounced on the ball after it was parried by Consigli from another Pirlo effort.
Sebastian Giovinco dragged a shot wide of the far post, was denied by Consigli and then struck another effort over the crossbar as he tried in vain to add his name to the scoresheet.