Premier League: Manchester City vs. Queens Park Rangers (live, Sunday, 8:30 a.m. ET)
Reasons to watch: Attention turns to the bottom of the Premier League this weekend. Only a win for QPR at the Etihad will delay their inevitable relegation from the Premier League after just one season in the top flight. City are virtually over the line by virtue of their superior goal difference over Liverpool but a point will make them mathematically certain of Champions League football next season. QPR proved they are no pushovers when the two sides met at Loftus Road in November when Sergio Aguero rescued a point for City seven minutes from time (Source: FOXSoccer.com's Warren Barner).
Getty ImagesTom Dulat
Premier League: Hull City vs. Burnley (live, Saturday, 10 a.m. ET)
Reasons to watch: Burnley's problems in front of goal have proved to be their Achilles heel this season and they, like QPR, must beat Hull City at the weekend if they are to keep their slim hopes of survival alive, otherwise an immediate return to the second tier beckons. Hull are not out of the mire by any means. Their two-game winning run came to an abrupt end against Arsenal on Monday and they could find themselves back in the bottom three if Sunderland win at Everton. Plenty at stake here so expect a cauldron-like atmosphere at the KC (Source: FOXSoccer.com's Warren Barner).
Getty ImagesChris Brunskill
Premier League: Crystal Palace vs. Manchester United (live, Saturday, 12:30 p.m. ET)
Reasons to watch: Manchester United are staring at a fourth defeat in a row as their quest for a top-four finish starts to unravel. The Red Devils' improbable home defeat last weekend against West Brom, a team with nothing to play for, has opened the door for Liverpool to sneak into the final UEFA Champions League place. Palace have been doing a bit of unraveling themselves having lost their last three games without scoring a goal. Alan Pardew will have his men pumped up for this one though and let's not forget what they did to Liverpool at the end of last season when Palace came back from three goals down to draw -- effectively ending the Reds' title hopes (Source: FOXSoccer.com's Warren Barner).
AFP/Getty ImagesOLI SCARFF
Championship Promotion Playoff: Ipswich Town vs. Norwich City (live, Saturday, 7:15 a.m. ET)
Reasons to watch: This is one of those derbies that rarely features in the lists of top ten rivalries but it certainly matters - and there's plenty at stake. These two clubs are in the Championship play-offs with a place in the Premier League at stake. They will play each other over two legs and the triumphant team will meet the winner of the other semi-final at Wembley in a one-off match. Untold riches ($150 million) will follow as a result of the new lucrative Premier League deal. Let battle commence (Source: FOXSoccer.com's Warren Barner).
Getty ImagesJamie McDonald
Serie A: AC Milan vs. Roma (live, Saturday, 2:45 p.m.)
Reasons to watch: Roma, who moved into second in the standings after last weekend's 2-0 victory over Genoa, face AC Milan and will look to earn an automatic Champions League berth at season's end. The Rossoneri, who remain sandwiched in the Serie A table, have an outside shot -- albeit a long one -- of capturing a Europa League spot if results go their way. Expect an action-packed match at the San Sire on Saturday (Source: Sky Sports).
AFP/Getty ImagesFILIPPO MONTEFORTE
Premier League: Chelsea vs. Liverpool (live, Sunday, 11 a.m. ET)
Reasons to watch: Steven Gerrard, whose mistake against Chelsea last season put Manchester City in the driving seat for the Premier League title, could have been one of the Chelsea players that will be given a guard of honor at Stamford Bridge this weekend. Instead, he rejected the Blues' overtures in pursuit of Premier League glory with the club he loves. Alas, that will never happen and he will join his teammates in applauding the champions and think about what have been. However, the Reds still have something to play for, although only a win against Mourinho's men will do if they are to remain with a chance of overhauling Manchester United. This should be a sizzling encounter.
AFP/Getty ImagesPAUL ELLIS
Serie A: Juventus vs. Cagliari (live, Saturday, 12 p.m. ET)
Reasons to watch: Newly-crowned Serie A champions Juventus head into Saturday's home game against Cagliari with one eye on next week's Champions League return leg at Real Madrid. The Bianconeri clinched their fourth successive scudetto with four games to spare last weekend with a 1-0 away triumph over Sampdoria. Juve boss Massimiliano Allegri is expected to rest his top players in view of next week's crunch game in Spain, although Paul Pogba is set to return to action (Source: Sky Sports).
Reasons to watch: Borussia Monchengladbach and Bayer Leverkusen go head-to-head in a game which could determine which of the two qualifies directly for the group stage of the Champions League next season and who has to go through a playoff. Needless to say, this one matters. Keep your eyes glued to the set as both clubs enter this highly-anticipated match in terrific form (Source: Sky Sports).
Bongarts/Getty ImagesDennis Grombkowski
La Liga: Real Madrid vs. Valencia (live, Saturday, 2 p.m. ET)
Reasons to watch: Real Madrid's game at the weekend is the reverse match from Jan. 4 when both Los Blancos and Barcelona famously lost to Valencia and Sociedad, respectively. The stakes are a lot higher now -- and not just for Carlo Ancelotti's men, who trail their Catalan rivals by two points. Fourth-placed Valencia are still chasing a Champions League place and are just three points ahead of Sevilla, who face mid-table Celta Vigo this weekend. It all makes for another fascinating La Liga matchday. This race is going right down to the wire (Source: FOXSoccer.com's Warren Barner).
Real Madrid via Getty ImagesVictor Carretero
La Liga: Barcelona vs. Real Sociedad (live, Saturday, 12 p.m. ET)
Reasons to watch: Barcelona are full of the joys of spring after a sensational Champions League semifinal win against Bayern Munich but they have no time to rest on their laurels. With just three games to go Barca are just two points of nearest rivals Real Madrid. However, Luis Enrique's men should be wary of Sociedad, who beat Barca in one of David Moyes' first games in charge in the New Year. Barca must win this game because a trip to current champions Atletico follows. Plenty of drama left in this title race, though it remains to be seen if the strike will derail those plans (Source: FOXSoccer.com's Warren Barner).